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172472

Sigma-Aldrich

Isopropylmyristat

98%

Synonym(e):

Isopropyl-myristat, Isopropyl-tetradecanoat

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About This Item

Lineare Formel:
CH3(CH2)12COOCH(CH3)2
CAS-Nummer:
110-27-0
Molekulargewicht:
270.45
Beilstein:
1781127
EG-Nummer:
203-751-4
MDL-Nummer:
MFCD00008982
UNSPSC-Code:
12352100
eCl@ss:
39022421
PubChem Substanz-ID:
24850403
NACRES:
NA.22

Assay

98%

Form

liquid

Brechungsindex

n20/D 1.434 (lit.)

bp

193 °C/20 mmHg (lit.)

mp (Schmelzpunkt)

~3 °C (lit.)

Dichte

0.85 g/mL at 25 °C (lit.)

SMILES String

CCCCCCCCCCCCCC(=O)OC(C)C

InChI

1S/C17H34O2/c1-4-5-6-7-8-9-10-11-12-13-14-15-17(18)19-16(2)3/h16H,4-15H2,1-3H3

InChIKey

AXISYYRBXTVTFY-UHFFFAOYSA-N

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Allgemeine Beschreibung

IPM is a fatty acid ester that can be produced by the esterification of isopropyl alcohol and myristic acid.

Anwendung

Isopropyl myristate was used as oil phase in the preparation of formulations. It was also used as oil/water-type tacrolimus (FK506) solvent.

Lagerklassenschlüssel

10 - Combustible liquids

WGK

awg

Flammpunkt (°F)

>302.0 °F

Flammpunkt (°C)

> 150 °C

Persönliche Schutzausrüstung

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Isopropylhexadecanoat European Pharmacopoeia (EP) Reference Standard

I0725000

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Timothy S McClintock et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(47), 15669-15678 (2014-11-21)
Our understanding of mammalian olfactory coding has been impeded by the paucity of information about the odorant receptors (ORs) that respond to a given odorant ligand in awake, freely behaving animals. Identifying the ORs that respond in vivo to a
Neslihan Ustündağ Okur et al.
Chemical & pharmaceutical bulletin, 62(2), 135-143 (2014-02-05)
Naproxen (Np) is an example of a non-steroidal anti-inflammatory drug (NSAID) commonly used for the reduction of pain and inflammation. In order to develop an alternative formulation for the topical administration of Np, microemulsions were evaluated as delivery vehicles. Four
Masayuki Yamanaka et al.
International journal of pharmaceutics, 464(1-2), 19-26 (2014-01-25)
We developed an oil/water-type tacrolimus (FK506) cream formulation as an alternative to Protopic ointment for atopic dermatitis treatment. We determined the effects of solvents used in topical preparations on FK506 solubility and stability, and evaluated FK506 transdermal absorption into rat
Ji Zhang et al.
International journal of pharmaceutics, 421(1), 34-44 (2011-10-01)
In this study, microemulsion microstructures, key formulation variables, and their relationship to drug transdermal permeation enhancement were investigated. A microemulsion system with high water soluble capacity was developed, using isopropyl myristate, Labrasol, and Cremophor EL as oil, surfactant, and co-surfactant
Qingping Tian et al.
International journal of pharmaceutics, 426(1-2), 202-210 (2012-01-26)
To improve the skin permeation of naproxen with larger dosage, microemulsion with high content of naproxen was investigated for transdermal delivery and its solubilization mechanism was studied. Naproxen micoremulsions composed of 4% isopropyl myristate, 18% Tween 80, 18% ethanol and
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