159255

2,2′,4′-Trichloracetophenon

97%

• Synonym(e): ω,2,4-Trichloracetophenon, 2,4-Dichlor-phenacylchlorid
• Lineare Formel: Cl₂C₆H₃COCH₂Cl
• CAS-Nummer: 4252-78-2
• Molekulargewicht: 223.48
• Beilstein: 957098
• EG-Nummer: 224-218-2
• MDL-Nummer: MFCD00000934
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 24849802
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 100
• Assay: 97%
• Form: solid
• bp: 130-135 °C/4 mmHg (lit.)
• mp (Schmelzpunkt): 47-54 °C (lit.)
• Funktionelle Gruppe: chloro; ketone
• SMILES String: ClCC(=O)c1ccc(Cl)cc1Cl
• InChI: 1S/C8H5Cl3O/c9-4-8(12)6-2-1-5(10)3-7(6)11/h1-3H,4H2
• InChIKey: VYWPPRLJNVHPEU-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

2,2′,4′-Trichloroacetophenone is an α-haloketone. It undergoes reduction to 2′,4′-dichloroacetophenone by glutathione-dependent cytosolic enzymes present in the liver, kidney and brain. It participates in the microwave induced N-alkylation of several azoles to afford the corresponding 1-(2′,4′-dichlorophenacyl)azoles.

Sicherheitshinweise

• Piktogramme: GHS05,GHS07
• Signalwort: Danger
• H-Sätze: H315,H317,H318,H335
• P-Sätze: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): 230.0 °F - closed cup
• Flammpunkt (°C): 110 °C - closed cup
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Faceshields, Gloves