142859

Difluoressigsäure

98%

• Synonym(e): 1,1-Difluoroacetic acid, 2,2-Difluoroacetic acid
• Lineare Formel: F₂CHCO₂H
• CAS-Nummer: 381-73-7
• Molekulargewicht: 96.03
• Beilstein: 1098588
• EG-Nummer: 206-839-0
• MDL-Nummer: MFCD00004220
• UNSPSC-Code: 12352106
• PubChem Substanz-ID: 24848539
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 200
• Assay: 98%
• Form: liquid
• Brechungsindex: n20/D 1.344 (lit.)
• bp: 132-134 °C (lit.)
• mp (Schmelzpunkt): −1 °C (lit.)
• Dichte: 1.526 g/mL at 25 °C (lit.)
• SMILES String: OC(=O)C(F)F
• InChI: 1S/C2H2F2O2/c3-1(4)2(5)6/h1H,(H,5,6)
• InChIKey: PBWZKZYHONABLN-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

Difluoroaceticacid is a monocarboxylic acid and an organofluorine compound. Difluoroaceticacid is easy-to-handle reagent, useful for obtaining difluoromethyl substituents. Difluoroacetic acid can be used asdifluoromethylating reagent for the direct C−H difluoromethylation ofheteroaromatic compounds.

Anwendung

Used in the preparation of 2-difluoromethylbenzimidazoles, -oxazoles and -thiazoles from ortho-substituted anilines mediated by triphenylphoshine.

Sicherheitshinweise

• Piktogramme: GHS05,GHS07
• Signalwort: Danger
• H-Sätze: H314,H332,H412
• P-Sätze: P261 - P273 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Gefahreneinstufungen: Acute Tox. 4 Inhalation - Aquatic Chronic 3 - Eye Dam. 1 - Skin Corr. 1A
• Lagerklassenschlüssel: 8A - Combustible corrosive hazardous materials
• WGK: WGK 3
• Flammpunkt (°F): 172.4 °F - closed cup
• Flammpunkt (°C): 78 °C - closed cup
• Persönliche Schutzausrüstung: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter