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NOS1

nitric oxide synthase 1 (neuronal)

Synonyme:
IHPS1, N-NOS, NC-NOS, NOS, bNOS, nNOS
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(4842) Summary: The protein encoded by this gene belongs to the family of nitric oxide synthases, which synthesize nitric oxide from L-arginine. Nitric oxide is a reactive free radical, which acts as a biologic mediator in several processes, including neurotransmission, and antimicrobial and antitumoral activities. In the brain and peripheral nervous system, nitric oxide displays many properties of a neurotransmitter, and has been implicated in neurotoxicity associated with stroke and neurodegenerative diseases, neural regulation of smooth muscle, including peristalsis, and penile erection. This protein is ubiquitously expressed, with high level of expression in skeletal muscle. Multiple transcript variants that differ in the 5' UTR have been described for this gene but the full-length nature of these transcripts is not known. Additionally, alternatively spliced transcript variants encoding different isoforms (some testis-specific) have been found for this gene.[provided by RefSeq, Feb 2011]
  • Mouse(18125) nitric oxide synthase 1, neuronal
  • Rat(24598) nitric oxide synthase 1, neuronal
  • Zebrafish(60658) nitric oxide synthase 1 (neuronal)
  • domestic cat(101100342) nitric oxide synthase 1 (neuronal)
  • cow(536132) nitric oxide synthase 1 (neuronal)
  • Horse(100051079) nitric oxide synthase 1 (neuronal)
  • dog(477498) nitric oxide synthase 1 (neuronal)
  • chicken(427721) nitric oxide synthase 1 (neuronal)
  • naked mole-rat(101711993) nitric oxide synthase 1 (neuronal)
  • Domestic Rabbit(100009243) nitric oxide synthase 1 (neuronal)
  • domestic guinea pig(100729682) nitric oxide synthase 1 (neuronal)

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Small Molecule - Antagonist

Produktnummer
Beschreibung
Spezies
(−)-Thalidomide, >98%, solid,
Spezies
human, mouse, rat
(+)-Thalidomide, ≥98% (HPLC), powder,
Spezies
human, mouse, rat
Ammonium-pyrrolidindithiocarbamat, ~99%,
Spezies
human
Melatonin, powder, ≥98% (TLC),
Spezies
human
(±)-Thalidomid, ≥98%, powder,
Spezies
human, mouse, rat

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-Nitrotyrosin-Antikörper, Upstate®, from rabbit,
Speziesreaktivität
all
Anwendung
immunocytochemistry
immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-Nitrotyrosin-Antikörper, Chemicon®, from rabbit,
Speziesreaktivität
all, human, mouse
Anwendung
immunohistochemistry
western blot
Anti-Nitrotyrosine antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Speziesreaktivität
wide range
Anwendung
ELISA
immunofluorescence

immunohistochemistry

microarray

western blot
Anti-Stickstoffmonoxid-Synthase-I-Antikörper, serum, Chemicon®,
Speziesreaktivität
human, monkey, mouse, rat, sheep
Anwendung
immunohistochemistry
western blot
Anti-Nitrotyrosin-Antikörper, Klon 1A6, clone 1A6, Upstate®, from mouse,
Speziesreaktivität
vertebrates
Anwendung
immunocytochemistry
immunohistochemistry

immunoprecipitation (IP)

western blot

Small Molecule - Inhibitor

Produktnummer
Beschreibung
Spezies
Spermidin -trihydrochlorid, ≥98% (TLC),
Spezies
human
4-Nitro-brenzkatechin, ≥96.0%,
Spezies
rat
5-Methyl-2-nitroanilin, 95%,
Spezies
rat
2,6-Di-tert-butyl-4-Methylphenol, ≥99.0% (GC), powder,
Spezies
rat, human
L-Arginin, from non-animal source, meets EP, USP testing specifications, suitable for cell culture, 98.5-101.0%,
Spezies
rat, human

Kits

Produktnummer
Beschreibung
Spezies
Nitric Oxide Synthase Detection System, Fluorimetric, sufficient for 200 reactions,
Spezies
human

Small Molecule - Precursor

Produktnummer
Beschreibung
Spezies
L-Arginin, from non-animal source, meets EP, USP testing specifications, suitable for cell culture, 98.5-101.0%,
Spezies
rat, human
L-Arginin, ,
Spezies
rat, human
L-Arginin, 99%, FCC, FG,
Spezies
rat, human
L-Arginin, reagent grade, ≥98%,
Spezies
rat, human
L-Arginin, BioUltra, ≥99.5% (NT),
Spezies
rat, human

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting mouse Nos1,
Spezies
mouse