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MBP

myelin basic protein

Synonyme:
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(4155) Summary: The protein encoded by the classic MBP gene is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system. However, MBP-related transcripts are also present in the bone marrow and the immune system. These mRNAs arise from the long MBP gene (otherwise called 'Golli-MBP') that contains 3 additional exons located upstream of the classic MBP exons. Alternative splicing from the Golli and the MBP transcription start sites gives rise to 2 sets of MBP-related transcripts and gene products. The Golli mRNAs contain 3 exons unique to Golli-MBP, spliced in-frame to 1 or more MBP exons. They encode hybrid proteins that have N-terminal Golli aa sequence linked to MBP aa sequence. The second family of transcripts contain only MBP exons and produce the well characterized myelin basic proteins. This complex gene structure is conserved among species suggesting that the MBP transcription unit is an integral part of the Golli transcription unit and that this arrangement is important for the function and/or regulation of these genes. [provided by RefSeq, Jul 2008]
  • Mouse(17196) myelin basic protein
  • Rat(24547) myelin basic protein
  • chicken(396217) myelin basic protein
  • domestic cat(101096421) myelin basic protein
  • dog(476160) myelin basic protein
  • cow(618684) myelin basic protein
  • naked mole-rat(101702488) myelin basic protein
  • domestic guinea pig(100731253) myelin basic protein
  • sheep(101109407) myelin basic protein

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Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Monoclonal Anti-MBP antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL2829, purified immunoglobulin, buffered aqueous glycerol solution,
Speziesreaktivität
human, mouse, rat
Anwendung
immunohistochemistry
western blot
Anti-Myelin Basic Protein Mouse mAb (SMI-99), liquid, clone SMI-99, Calbiochem®,
Speziesreaktivität
guinea pig, mammals
Anwendung
Monoclonal Anti-MBP antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL2827, purified immunoglobulin, buffered aqueous glycerol solution,
Speziesreaktivität
human, mouse, rat
Anwendung
immunofluorescence
immunohistochemistry

western blot
Anti-MBP, affinity isolated antibody,
Speziesreaktivität
dog, guinea pig, horse, human, rabbit, rat
Anwendung
western blot
Monoclonal Anti-Myelin Basic Protein (MBP) (36-50) antibody produced in rat, clone 14, tissue culture supernatant,
Speziesreaktivität
chicken, horse, human
Anwendung
ELISA
immunofluorescence

immunohistochemistry

Proteins

Produktnummer
Beschreibung
Spezies
Myelin-basisches Protein Rind, ≥90% (SDS-PAGE), lyophilized powder, suitable for activity assay,
Spezies
cow
Myelin Basic Protein Antigen from human brain, ≥95% (SDS-PAGE),
Spezies
human
MBP, dephosphoryliert, ,
Spezies
cow
MBP (basischen Myelinprotein), Rind, aufgereinigt, ,
Spezies
cow
Myelin Basic Protein from guinea pig brain, ≥80% (SDS-PAGE), lyophilized powder, from guinea pig brain,
Spezies
domestic guinea pig

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human MBP,
Spezies
human