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HRH1

histamine receptor H1

Synonyme:
H1-R, hisH1
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(3269) Summary: Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. This gene was thought to be intronless until recently. The protein encoded by this gene is an integral membrane protein and belongs to the G protein-coupled receptor superfamily. It mediates the contraction of smooth muscles, the increase in capillary permeability due to contraction of terminal venules, the release of catecholamine from adrenal medulla, and neurotransmission in the central nervous system. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
  • Mouse(15465) histamine receptor H1
  • Rat(24448) histamine receptor H 1
  • Zebrafish(735302) histamine receptor H1
  • dog(403813) histamine receptor H1
  • domestic cat(101088314) histamine receptor H1
  • cow(281231) histamine receptor H1
  • Horse(100034110) histamine receptor H1
  • chicken(100858928) histamine receptor H1
  • domestic guinea pig(100135539) histamine receptor H1
  • domestic guinea pig(100730517) histamine receptor H1
  • naked mole-rat(101715481) histamine receptor H1
  • sheep(101121717) histamine receptor H1

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Small Molecule - Agonist

Produktnummer
Beschreibung
Spezies
Histamin -dihydrochlorid, ≥99.0% (AT),
Spezies
human
Histamin, analytical standard,
Spezies
human
Histamin -dihydrochlorid, United States Pharmacopeia (USP) Reference Standard,
Spezies
human
Histamin, European Pharmacopoeia (EP) Reference Standard,
Spezies
human
Histamin -dihydrochlorid, European Pharmacopoeia (EP) Reference Standard,
Spezies
human

Small Molecule - Antagonist

Produktnummer
Beschreibung
Spezies
Pheniraminmaleat, United States Pharmacopeia (USP) Reference Standard,
Spezies
human
Diphenhydramin -hydrochlorid, ≥98% (HPLC),
Spezies
human
Cetirizin -dihydrochlorid, ≥98% (HPLC),
Spezies
human
Promethazin -hydrochlorid, ,
Spezies
human
Chlorpheniraminmaleat, United States Pharmacopeia (USP) Reference Standard,
Spezies
human

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Monoclonal Anti-HRH1 antibody produced in mouse, clone 3D1, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
ELISA
proximity ligation assay
Anti-Histaminrezeptor 1-Antikörper, CT, Chemicon®, from rabbit,
Speziesreaktivität
bovine, mouse, rat
Anwendung
ELISA
western blot

Small Molecule - Blocker

Produktnummer
Beschreibung
Spezies
Cinnarizin, European Pharmacopoeia (EP) Reference Standard,
Spezies
human
Mianserin -hydrochlorid, ,
Spezies
human
Cinnarizin, powder,
Spezies
human
Orphenadrin -hydrochlorid, ≥98.0% (AT),
Spezies
human
Orphenadrin für die Peakidentifizierung, European Pharmacopoeia (EP) Reference Standard,
Spezies
human

Small Molecule - Inhibitor

Produktnummer
Beschreibung
Spezies
Ketotifen -fumarat (Salz), ,
Spezies
human
L-Histidin -dihydrochlorid, ≥98 (TLC),
Spezies
mouse, rat, human
D-Histidin -monohydrochlorid Monohydrat, ≥98% (TLC),
Spezies
mouse, rat, human
Loratadin, ≥98% (HPLC), powder,
Spezies
rat, human
Histamin, ≥97.0%,
Spezies
human, rat

Small Molecule - Ligand

Produktnummer
Beschreibung
Spezies
Loratadin, ≥98% (HPLC), powder,
Spezies
rat, human
Cinnarizin, powder,
Spezies
human

Small Molecule - Metabolite

Produktnummer
Beschreibung
Spezies
1-Methylhistamin -dihydrochlorid, ≥98% (TLC), powder,
Spezies
human

Small Molecule - Mixed Agonist/Antagonist

Produktnummer
Beschreibung
Spezies
2-(2-Pyridyl)ethylamin, 95%,
Spezies
human
Haloperidol, powder,
Spezies
human, rat
Clozapin, ,
Spezies
human, rat

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting mouse Hrh1,
Spezies
mouse
MISSION® esiRNA, targeting human HRH1,
Spezies
human