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APP

amyloid beta (A4) precursor protein

Synonyme:
AAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN-II, PN2
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(351) Summary: This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(11820) amyloid beta (A4) precursor protein
  • Rat(54226) amyloid beta (A4) precursor protein
  • fruit fly(39399) approximated
  • chicken(374198) amyloid beta (A4) precursor protein
  • domestic cat(101085564) amyloid beta (A4) precursor protein
  • cow(280722) amyloid beta (A4) precursor protein
  • dog(403407) amyloid beta (A4) precursor protein
  • naked mole-rat(101724743) amyloid beta (A4) precursor protein
  • domestic guinea pig(100715302) amyloid beta (A4) precursor protein
  • sheep(101111593) amyloid beta (A4) precursor protein

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ELISA

Produktnummer
Beschreibung
Spezies
Hochsensitiver ELISA für humanes Amyloid β42, This High Sensitivity Human Amyloid β42 ELISA is used to measure & quantify Amyloid β42 levels in Neuroscience research.,
Spezies
human
Human APP / Amyloid Beta A4 Protein ELISA Kit, for serum, plasma, cell culture supernatants and urine,
Spezies
human
Hochsensitiver ELISA für humanes Amyloid β42 im Gehirn, This Human Amyloid β42 Brain ELISA is used to measure & quantify Amyloid β42 levels in Neuroscience research.,
Spezies
human
Hochsensitiver ELISA für humanes Amyloid β40, This High Sensitivity Human Amyloid β40 ELISA is used to measure & quantify Amyloid β40 levels in Neuroscience research.,
Spezies
human

Small Molecule - Antagonist

Produktnummer
Beschreibung
Spezies
BTA-1, ≥98% (HPLC), solid,
Spezies
human
Curcumin, from Curcuma longa (Turmeric), powder,
Spezies
human
Curcumin, ≥94% (curcuminoid content), ≥80% (Curcumin),
Spezies
human
Flurbiprofen, cyclooxygenase inhibitor,
Spezies
human, rat

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-APP-A4-Antikörper, a.a. 66-81 von APP {NT}, Klon 22C11, clone 22C11, Chemicon®, from mouse,
Speziesreaktivität
canine, fish, human, monkey, mouse, pig, rat
Anwendung
immunofluorescence
immunohistochemistry

western blot
Anti-Beta-Amyloid 1-42-Antikörper, Chemicon®, from rabbit,
Speziesreaktivität
chicken, human, mouse
Anwendung
ELISA
immunohistochemistry

western blot
Anti-Amyloid-β-Antikörper, Klon W0-2, clone WO2, from mouse,
Speziesreaktivität
human, mouse
Anwendung
ELISA
immunohistochemistry

western blot
Anti-Amyloid-Oligomer-Antikörper, αβ, oligomerisch, serum, Chemicon®,
Speziesreaktivität
eukaryotes, human, mouse, rat
Anwendung
ELISA
immunofluorescence

immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-β-Amyloid-Antikörper, monoklonaler Antikörper der Maus in Maus hergestellte Antikörper, clone NAB 228, purified from hybridoma cell culture,
Speziesreaktivität
human
Anwendung
ELISA
immunohistochemistry

immunoprecipitation (IP)

microarray

western blot

Proteins

Produktnummer
Beschreibung
Spezies
Amyloid-β-Proteinfragment 1-42, ,
Spezies
human
Amyloid-β-Proteinfragment 25-35, ≥97% (HPLC),
Spezies
human
Amyloid β Protein Fragment 1-40, ≥90% (HPLC), powder,
Spezies
human
β Amyloid 1-42, aβ, ultra pure, HFIP, recombinant human, ,
Spezies
human
β Amyloid 1-42, aβ, ultra pure, TFA, recombinant human, ,
Spezies
human

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human APP,
Spezies
human
MISSION® esiRNA, targeting mouse App,
Spezies
mouse