T5134

(±)-α-Tocopherol nicotinate

• Synonyme(s) : Vitamin E nicotinate
• Formule empirique (notation de Hill): C₃₅H₅₃NO₃
• Numéro CAS: 51898-34-1
• Poids moléculaire : 535.80
• Numéro CE : 257-501-4
• Numéro MDL: MFCD03548047
• Code UNSPSC : 12352211
• ID de substance PubChem : 24900260
• Nomenclature NACRES : NA.79

Propriétés

• Essai: ≥98%
• Niveau de qualité: 100
• Forme: solid or liquid
• Couleur: white to yellow
• Température de stockage: 2-8°C
• Chaîne SMILES: CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC[C@]1(C)CCc2c(C)c(OC(=O)c3cccnc3)c(C)c(C)c2O1
• InChI: 1S/C35H53NO3/c1-24(2)13-9-14-25(3)15-10-16-26(4)17-11-20-35(8)21-19-31-29(7)32(27(5)28(6)33(31)39-35)38-34(37)30-18-12-22-36-23-30/h12,18,22-26H,9-11,13-17,19-21H2,1-8H3/t25-,26-,35-/m1/s1
• Clé InChI: MSCCTZZBYHQMQJ-AZAGJHQNSA-N

Description

Description générale

α-Tocopherol nicotinate is a fat soluble vitamin. It is an ester of tocopherol and niacin. Niacin is linked to the hydroxyl group of active vitamin E in this ester. α-Tocopherol is a form of vitamin E, which is available through dietary sources. RRR-α-tocopherol is a natural form of α-Tocopherol.

Application

(±)-α-Tocopherol nicotinate has been used in metabolic studies to assess its biological functions in rats.

Actions biochimiques/physiologiques

α-Tocopherol is a radical-chain breaker owing to its anti-oxidant property.

Tocopherols (TCP) (vitamin E) are a series (α, β, γ and δ) of chiral organic molecules that vary in their degree of methylation of the phenol moiety of the chromanol ring. Tocopherols are lipid soluble anti-oxidants that protect cell membranes from oxidative damage. α-Tocopherol is the form of tocopherol preferentially absorbed by homo sapiens. α-Tocopherol nicotinate is used along the α-Tocopherol acetate, α-Tocopherol succinate and other esterified forms as a vitamin E supplement with similar but differential activities.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)