SRP8048

PEDF mouse

recombinant, expressed in CHO cells, FLAG^® tagged, >95% (SDS-PAGE)

• Synonyme(s) : Caspin, PC cell-derived growth factor, Pigment epithelium-derived factor, Stromal cell-derived factor 3
• Numéro CAS: 607410-75-3
• Code UNSPSC : 12352202
• Nomenclature NACRES : NA.32

Propriétés

• Source biologique: mouse
• Produit recombinant: expressed in CHO cells
• Étiquette/Marqueur: FLAG^® tagged
• Pureté: >95% (SDS-PAGE)
• Forme: lyophilized
• Poids mol.: ~47 kDa by SDS-PAGE
• Conditionnement: pkg of 10 μg
• Conditions de stockage: avoid repeated freeze/thaw cycles
• Impuretés: <0.01 EU/μg endotoxin, tested
• Couleur: white
• Numéro d'accès UniProt: P97298
• Conditions d'expédition: wet ice
• Température de stockage: −20°C
• Informations sur le gène: mouse ... Serpinf1(20317)

Description

Description générale

Pigment epithelium-derived factor (PEDF) is a 47kDa secreted glycoprotein that belongs to the non-inhibitory serpin family group. PEDF is widely expressed in adult and fetal tissues, including brain, spinal cord, plasma, bone, prostate, pancreas, heart and lung. PEDF acts as an angiogenesis inhibitor with neurotrophic, immunomodulation and antitumor properties. It functions as anti-angiogenic agent by counterbalancing the proangiogenic effect of VEGF. PEDF is one of the most abundant proteins released by adipocytes and induces insulin resistance in adipocytes and human skeletal muscle cells. Recently, it has been reported that PEDF is sufficient to maintain the self-renewal of pluripotent human embryonic stem cells.

Forme physique

Lyophilized from PBS.

Reconstitution

Reconstitute with 100 μL deionized water.

Autres remarques

Mouse PEDF (aa 20-417) is fused at the C-terminus to a FLAG^®-tag.

Informations légales

FLAG is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable