SRP8046

Netrin-1 (human): FC (human)

recombinant, expressed in HEK 293 cells, >95% (SDS-PAGE)

• Synonyme(s) : ACRP30headless:TNFSF13, NTN1
• Code UNSPSC : 12352200
• Nomenclature NACRES : NA.32

Propriétés

• Source biologique: human
• Produit recombinant: expressed in HEK 293 cells
• Pureté: >95% (SDS-PAGE)
• Forme: lyophilized
• Poids mol.: ~90 kDa by SDS-PAGE
• Conditionnement: pkg of 10 μg
• Conditions de stockage: avoid repeated freeze/thaw cycles
• Impuretés: <0.1 EU/μg endotoxin, tested
• Couleur: white
• Numéro d'accès UniProt: O95631
• Conditions d'expédition: wet ice
• Température de stockage: −20°C
• Informations sur le gène: human ... NTN1(9423)

Description

Description générale

Netrin-1 controls guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. It also serve as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Netrin 1 is also Involved in tumorigenesis by regulating apoptosis.

Forme physique

Lyophilized from PBS with trehalose and Brij35.

Reconstitution

Reconstitute with 100 μL deionized water.

Autres remarques

Human netrin-1 (aa 25-604) is fused at the C-terminus to the Fc portion of human IgG1.

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable