SAB5700294

Anti-Phospho-EIF4EBP1-T37/46 antibody produced in rabbit

• Synonyme(s) : 4E-BP1, 4EBP1, BP-1, EIF4EBP1, PHAS-I
• Code UNSPSC : 12352203
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rabbit
• Niveau de qualité: 100
• Forme d'anticorps: affinity isolated antibody
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Forme: buffered aqueous solution
• Poids mol.: 12
• Espèces réactives: human, mouse
• Concentration: 1.23 mg/ml
• Technique(s): western blot: 1:500-1:2000
• Numéro d'accès UniProt: Q13541
• Conditions d'expédition: wet ice
• Température de stockage: −20°C
• Modification post-traductionnelle de la cible: phosphorylation (pThr37/pThr46)
• Informations sur le gène: human ... EIF4EBP1(1978)

Description

Description générale

This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5′ end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.

Immunogène

A phospho specific peptide corresponding to residues surrounding T37/46 of human EIF4EBP1

Forme physique

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Stockage et stabilité

Store at -20℃. Avoid freeze / thaw cycles.

Informations sur la sécurité

• Code de la classe de stockage: 12 - Non Combustible Liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable