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S1002

Sigma-Aldrich

Saccharine sodium salt hydrate

≥98.0% (titration)

Synonyme(s) :

2,3-dihydro-3-oxobenzisosulfonazole sodium salt, o-sulfobenzimide sodium salt, Saccharine soluble

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About This Item

Formule empirique (notation de Hill):
C7H4NNaO3S · xH2O
Numéro CAS:
82385-42-0
Poids moléculaire :
205.17 (anhydrous basis)
Numéro Beilstein :
3599229
Numéro CE :
204-886-1
Numéro MDL:
MFCD00149605
Code UNSPSC :
12164504
ID de substance PubChem :
24899456
Nomenclature NACRES :
NA.25

Pureté

≥98.0% (titration)

Sucrosité

300 × sucrose

Chaîne SMILES 

[Na+].[H]O[H].[O-]C1=NS(=O)(=O)c2ccccc12

InChI

1S/C7H5NO3S.Na.H2O/c9-7-5-3-1-2-4-6(5)12(10,11)8-7;;/h1-4H,(H,8,9);;1H2/q;+1;/p-1

Clé InChI

ILJOYZVVZZFIKA-UHFFFAOYSA-M

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Application


  • Application of a colorimetric technique in quality control for printed pediatric orodispersible drug delivery systems containing propranolol hydrochloride.: This article discusses the use of a colorimetric method to ensure quality control in 3D printed pediatric drug delivery systems, incorporating saccharin sodium salt hydrate as a sweetener, emphasizing its role in improving the taste and compliance of pediatric medications (Vakili et al., 2016).

Actions biochimiques/physiologiques

′First generation′ synthetic sugar alternative that has been studied for its carcinogenic potential.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)

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Robert A Boakes et al.
Physiology & behavior, 218, 112822-112822 (2020-02-01)
Rats first given 24-h access to 10% sucrose for 4 or 12 days (Stage 1) were then switched to a saccharin solution for a 12-day Stage 2. The initial result of this switch was that these Sucrose groups drank less
Simone Rehn et al.
Physiology & behavior, 207, 15-27 (2019-05-06)
When animals are given access to a palatable food or drink on some days but not on others, the amount they consume can far exceed the daily amounts consumed by controls given daily access. A previous study demonstrated such bingeing
Valentina Sabino et al.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 34(6), 1482-1493 (2008-10-24)
Sigma-Receptors (SigRs) have been implicated in behavioral and appetitive effects of psychostimulants and may also modulate the motivating properties of ethanol. This study tested the hypothesis that SigRs modulate ethanol reinforcement and contribute to excessive ethanol intake. The effects of
Deirdre M McCarthy et al.
Scientific reports, 10(1), 11974-11974 (2020-07-21)
The use of non-nutritive sweeteners such as saccharin is widely prevalent. Although saccharin is considered safe for human consumption, it produces behavioral changes in experimental animals. We report that saccharin's behavioral effects are much more pervasive than currently recognized. In
Rhian Alice Ceredig et al.
Frontiers in molecular neuroscience, 12, 324-324 (2020-03-03)
Neuropathic pain is a challenging condition for which current therapies often remain unsatisfactory. Chronic administration of β2 adrenergic agonists, including formoterol currently used to treat asthma and chronic obstructive pulmonary disease, alleviates mechanical allodynia in the sciatic nerve cuff model
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