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Neotame

analytical standard

Synonyme(s) :

N-[N-(3,3-Dimethylbutyl)-L-α-aspartyl]-L-phenylalanine 1-methyl ester

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About This Item

Formule empirique (notation de Hill):
C20H30N2O5
Numéro CAS:
Poids moléculaire :
378.46
Numéro Beilstein :
8352678
Numéro MDL:
Code UNSPSC :
85151701
ID de substance PubChem :
Numéro E:
E961
Nomenclature NACRES :
NA.24

Qualité

analytical standard

Niveau de qualité

Pureté

≥98.0% (HPLC)

Activité optique

[α]/D -41.0±3.0°, c = 0.5 in H2O

Durée de conservation

limited shelf life, expiry date on the label

Technique(s)

HPLC: suitable
gas chromatography (GC): suitable

Application(s)

cleaning products
cosmetics
food and beverages
personal care

Format

neat

Chaîne SMILES 

COC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(O)=O)NCCC(C)(C)C

InChI

1S/C20H30N2O5/c1-20(2,3)10-11-21-15(13-17(23)24)18(25)22-16(19(26)27-4)12-14-8-6-5-7-9-14/h5-9,15-16,21H,10-13H2,1-4H3,(H,22,25)(H,23,24)/t15-,16-/m0/s1

Clé InChI

HLIAVLHNDJUHFG-HOTGVXAUSA-N

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Description générale

Neotame is a white colored, dipeptide methyl ester, which is found to be a highly potent and non-nutritive sweetener or flavour enhancer and hence finds applications in variety of foods. It is manufactured from aspartame and 3,3-dimethylbutyraldehyde in a one-step chemical synthesis process.
Neotame is chemically related to aspartame, an artificial sweetener, used in the production of sugar-free low-calorie foodstuffs. It is approved as a food additive depending upon the food or beverage application.

Application

Neotame may be used as an analytical reference standard for the quantification of the analyte in the following:
  • Wine samples using reversed-phase high-performance liquid chromatography (RP-HPLC).
  • Wastewaters using hydrophilic interaction liquid chromatography (HILIC).
  • Food samples using high-performance liquid chromatography (HPLC).

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Conditionnement

Bottomless glass bottle. Contents are inside inserted fused cone.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


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Certificats d'analyse (COA)

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Modifying the temporal profile of the high-potency sweetener neotame
Prakash I, et al.
Journal of Agricultural and Food Chemistry, 49, 786-789 (2001)
Neotame: discovery, properties, utility
Nofre C and Tinti M-J
Food Chemistry, 69, 245-257 (2000)
Joint RAO/WHO Expert Committee on Food Additives, World Health Organization
Evaluation of Certain Food Additives: Seventy-first Report of the Joint FAO/WHO Expert Committee on Food Additives (2004)
Yong-Gang Zhao et al.
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 28(10), 967-971 (2012-10-13)
A reversed-phase high-performance liquid chromatography (RP-HPLC) method was developed for the simultaneous determination of nine food additives, i.e., acesulfame, saccharin, caffeine, aspartame, benzoic acid, sorbic acid, stevioside, dehydroacetic acid and neotame in red wine. The effects of ion-suppressors, i.e.

Protocoles

RP-Amide and HILIC, both amenable to the analysis of polar compounds, were successfully used to resolve several beverage components, including sugars, vitamins, sweeteners, preservatives, and caffeine.

Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..

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