L9150

N-Lauroylsarcosine sodium salt

detergent for use in cell lysis

• Synonyme(s) : Sodium lauroyl sarcosinate, N-Dodecanoyl-N-methylglycine sodium salt, Sarkosyl NL
• Formule linéaire : CH₃(CH₂)₁₀CON(CH₃)CH₂COONa
• Numéro CAS: 137-16-6
• Poids moléculaire : 293.38
• Numéro Beilstein : 5322974
• Numéro CE : 205-281-5
• Numéro MDL: MFCD00042728
• Code UNSPSC : 12161902
• ID de substance PubChem : 57654340
• Nomenclature NACRES : NA.52

Propriétés

• Qualité: for molecular biology
• Niveau de qualité: 200
• Description: anionic
• Gamme de produits: BioReagent
• Pureté: ≥94%
• Forme: powder
• Poids mol.: micellar avg mol wt 600
• Nombre d'agrégation: 2
• Technique(s): protein purification: suitable; protein quantification: suitable
• CMC: 14.6 mM (20-25°C)
• Solubilité: H₂O: 100 mg/mL, clear to slightly hazy, colorless to faintly yellow
• Activité étrangère: DNase, RNase, none detected
• Température de stockage: room temp
• Chaîne SMILES: [Na+].CCCCCCCCCCCC(=O)N(C)CC([O-])=O
• InChI: 1S/C15H29NO3.Na/c1-3-4-5-6-7-8-9-10-11-12-14(17)16(2)13-15(18)19;/h3-13H2,1-2H3,(H,18,19);/q;+1/p-1
• Clé InChI: KSAVQLQVUXSOCR-UHFFFAOYSA-M

Description

Description générale

Sodium lauroyl sarcosinate, the sodium salt of an acyl derivative of sarcosine—a natural amino acid occurring in muscles and body tissues—stands out as a valuable component in molecular biology, biochemical, and cell biology research. Derived from a natural fatty acid and the amino acid derivative sarcosine, N-Lauroylsarcosine is a biodegradable anionic surfactant usually synthesized through acylation and neutralization reactions involving lauric acid and sodium sarcosine.

This amino acid-type anionic surfactant, also recognized as a fatty acid amide and detergent, exhibits protein denaturant potency and has been integrated into lysing solutions, such as the cornet assay. Its application extends to lysing protoplasts for chromosomal DNA isolation from Streptococcus mutans. Notably, Lauroylsarcosine Sodium Salt, characterized by its ionic detergent properties, is commonly employed for purifying membrane proteins. Additionally, Sodium Lauroyl Sarcosine also plays a crucial role in concentrated salt solutions, facilitating cell lysis in RNA purification protocols and membrane solubilization. Whether it′s breaking down cell structures or facilitating membrane protein purification, this mild surfactant proves valuable in various applications within the realms of biology and biochemistry.

Application

Suitable for

• solubilization and separation of membrane proteins
• lysis of cells during the isolation of RNA
• inhibition of hexokinase

Caractéristiques et avantages

• Suitable for Molecular Biology, Biochemical and Cell Biology research
• Can be used for Protein Purification and Quantification
• High purity product for research applications

Autres remarques

Anionic surfactant.

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Informations sur la sécurité

• Pictogrammes: GHS05,GHS06
• Mention d'avertissement: Danger
• Mentions de danger: H315 - H318 - H330
• Conseils de prudence: P260 - P264 - P280 - P302 + P352 - P304 + P340 + P310 - P305 + P351 + P338
• Classification des risques: Acute Tox. 2 Inhalation - Eye Dam. 1 - Skin Irrit. 2
• Code de la classe de stockage: 6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): 512.6 °F - closed cup
• Point d'éclair (°C): 267 °C - closed cup
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)