H4628

DL-Homocysteine

≥95% (titration)

• Synonyme(s) : 2-Amino-4-mercaptobutyric acid
• Formule linéaire : HSCH₂CH₂CH(NH₂)COOH
• Numéro CAS: 454-29-5
• Poids moléculaire : 135.18
• Numéro Beilstein : 1721683
• Numéro CE : 207-222-9
• Numéro MDL: MFCD00004898
• Code UNSPSC : 12352209
• eCl@ss : 42021308
• ID de substance PubChem : 24895646
• Nomenclature NACRES : NA.26

Propriétés

• product name: DL-Homocysteine, ≥95% (titration)
• Niveau de qualité: 200
• Pureté: ≥95% (titration)
• Forme: powder
• Pf: 232-233 °C (lit.)
• Solubilité: H₂O: soluble
• Application(s): cell analysis; peptide synthesis
• Température de stockage: −20°C
• Chaîne SMILES: NC(CCS)C(O)=O
• InChI: 1S/C4H9NO2S/c5-3(1-2-8)4(6)7/h3,8H,1-2,5H2,(H,6,7)
• Clé InChI: FFFHZYDWPBMWHY-UHFFFAOYSA-N

Description

Application

DL-Homocysteine has been used to induce hyperhomocysteinemia in Sprague–Dawley rats. It has also been used to study the effects of hyperhomocysteinemia on atherosclerosis in apolipoprotein E-deficient mice.

Actions biochimiques/physiologiques

Homocysteine is a sulfhydryl-containing amino acid, synthesized from methionine. It is a non-essential, non-proteinogenic amino acid. It is an important determinant of the methylation cycle and is present in the plasma in four forms. An abnormally high level of homocysteine leads to hyperhomocysteinemia and also promotes atherosclerosis.

Increased plasma homocysteine is a risk factor for coronary heart disease and carcinogenesis; may be a marker for tumor cell growth.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)