69453
L-Homocysteine
≥98.0% (NT)
Synonyme(s) :
(S)-2-Amino-4-mercaptobutyric acid
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About This Item
Formule linéaire :
HSCH2CH2CH(NH2)COOH
Numéro CAS:
Poids moléculaire :
135.18
Numéro CE :
Numéro MDL:
Code UNSPSC :
12352204
ID de substance PubChem :
Nomenclature NACRES :
NA.32
Produits recommandés
Nom du produit
L-Homocysteine, ≥98.0% (NT)
Niveau de qualité
Essai
≥98.0% (NT)
Forme
powder
Activité optique
[α]/D 25.5±1.5°, c = 1 in 1 M HCl
Couleur
white
Pf
263-265 °C
Application(s)
cell analysis
Maladie(s) pertinente(s)
Alzheimer′s disease
Température de stockage
−20°C
Chaîne SMILES
N[C@@H](CCS)C(O)=O
InChI
1S/C4H9NO2S/c5-3(1-2-8)4(6)7/h3,8H,1-2,5H2,(H,6,7)/t3-/m0/s1
Clé InChI
FFFHZYDWPBMWHY-VKHMYHEASA-N
Description générale
L-homocysteine is used to diagnose homocystinuria.
Application
L-homocysteine has been used as a supplement in cell culture media.
Actions biochimiques/physiologiques
Elevated homocysteine levels in plasma and tissue are associated with brain atrophy in Alzheimer′s disease as well as in healthy eldery subjects. Increased homocysteine is due to deficiencies in vitamin B status, specifically folate, B6 and B12 vitamins, which act as cofactors for enzymes involved in homocysteine metabolism.
Conditionnement
Bottomless glass bottle. Contents are inside inserted fused cone.
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Les clients ont également consulté
Assessment of homocysteine status
Refsum H, et al.
Journal of inherited metabolic disease, 20(2), 286-294 (1997)
Arpita Basu et al.
Atherosclerosis, 236(1), 188-195 (2014-07-27)
Plasma total homocysteine (tHcy) has been positively associated with carotid intima-media thickness (IMT) in non-diabetic populations and in a few cross-sectional studies of diabetic patients. We investigated cross-sectional and prospective associations of a single measure of tHcy with common and
Ioana Cotlarciuc et al.
Stroke, 45(7), 1920-1924 (2014-05-23)
Elevated total plasma homocysteine (tHcy) levels are known to be associated with increased risk of ischemic stroke (IS). Given that both tHcy and IS are heritable traits, we investigated a potential genetic relationship between homocysteine levels and stroke risk by
James J H Chong et al.
Journal of the American Heart Association, 8(1), e011028-e011028 (2019-01-01)
Background Neutrophil gelatinase-associated lipocalin ( NGAL ) or lipocalin 2 may promote atherosclerosis and plaque instability leading to increased risk of cardiac events. We investigated the relationships between plasma NGAL , cardiovascular disease biomarkers, and long-term cardiac events. Methods and
Rajendra P Shukla et al.
Advanced healthcare materials, 8(15), e1900462-e1900462 (2019-06-27)
The antipsychotic clozapine is the most effective medication available for schizophrenia and it is the only antipsychotic with a known efficacious clinical range. However, it is dramatically underutilized due to the inability to test clozapine blood levels in finger-pricked patients'
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