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Key Documents

441R-1

Sigma-Aldrich

NKX3.1 (EP356) Rabbit Monoclonal Primary Antibody

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About This Item

Code UNSPSC :
12352203
Nomenclature NACRES :
NA.41

Source biologique

rabbit

Niveau de qualité

100
500

Conjugué

unconjugated

Forme d'anticorps

culture supernatant

Type de produit anticorps

primary antibodies

Clone

EP356, monoclonal

Description

(For In Vitro Diagnostic Use in Select Regions (See Chart))

Forme

buffered aqueous solution

Espèces réactives

human

Conditionnement

bottle of 1.0 mL predilute (441R-17)
bottle of 7.0 mL predilute (441R-18)
vial of 0.1 mL concentrate (441R-14)
vial of 0.5 mL concentrate (441R-15)
vial of 1.0 mL concentrate (441R-16)

Fabricant/nom de marque

Cell Marque

Technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200

Isotype

IgG

Conditions d'expédition

wet ice

Température de stockage

2-8°C

Informations sur le gène

human ... NKX3-1(4824)

Description générale

NKX3.1 is a prostate-specific androgen-regulated homeobox gene located on chromosome8p.1-2 NKX3.1 expression is seen in benign and malignant prostate epithelium. NKX3.1is a sensitive and specific tissue marker that can be used to help identify prostateadenocarcinoma.

Qualité


IVD

IVD

IVD

RUO

Liaison

NKX3.1 Positive Control Slides, Product No. 441S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Forme physique

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

Notes préparatoires

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Autres remarques

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Informations légales

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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Code de la classe de stockage

12 - Non Combustible Liquids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Rebecca J Asch-Kendrick et al.
Journal of clinical pathology, 67(9), 768-771 (2014-07-06)
NKX3.1 is an androgen-regulated tumour suppressor gene that is downregulated in prostate carcinoma. Immunohistochemistry for NKX3.1 is primarily specific for prostatic-derived tumours and tissue but is reported in a small number of breast carcinomas. NKX3.1 is also shown to inhibit
Ai-Ying Chuang et al.
The American journal of surgical pathology, 31(8), 1246-1255 (2007-08-02)
The histologic distinction between high-grade prostate cancer and infiltrating high-grade urothelial cancer may be difficult, and has significant implications because each disease may be treated very differently (ie, hormone therapy for prostate cancer and chemotherapy for urothelial cancer). Immunohistochemistry of
Bora Gurel et al.
The American journal of surgical pathology, 34(8), 1097-1105 (2010-07-01)
NKX3.1 is a prostatic tumor suppressor gene located on chromosome 8p. Although most studies have shown that staining for NKX3.1 protein is positive in the majority of primary prostatic adenocarcinomas, it has been shown to be downregulated in many high-grade

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