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30058

Sigma-Aldrich

Lipase Substrate

≥95% (HPLC)

Synonyme(s) :

1,2-Di-O-lauryl-rac-glycero-3-(glutaric acid 6-methylresorufin ester)

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About This Item

Formule empirique (notation de Hill):
C45H69NO8
Numéro CAS:
195833-46-6
Poids moléculaire :
752.03
Numéro MDL:
MFCD08276995
Code UNSPSC :
12352204
ID de substance PubChem :
57648405
Nomenclature NACRES :
NA.83

Niveau de qualité

100

Pureté

≥95% (HPLC)

Forme

powder

Solubilité

ethanol: soluble (10mg/mL)

Fluorescence

λex 529 nm; λem 600 nm in 0.1 M Tris pH 8.4

Température de stockage

2-8°C

Chaîne SMILES 

CCCCCCCCCCCCOCC(COC(=O)CCCC(=O)Oc1ccc2N=C3C=CC(=O)C(C)=C3Oc2c1)OCCCCCCCCCCCC

InChI

1S/C45H69NO8/c1-4-6-8-10-12-14-16-18-20-22-31-50-34-38(51-32-23-21-19-17-15-13-11-9-7-5-2)35-52-43(48)25-24-26-44(49)53-37-27-28-39-42(33-37)54-45-36(3)41(47)30-29-40(45)46-39/h27-30,33,38H,4-26,31-32,34-35H2,1-3H3

Clé InChI

FYOMYGYHAZESGQ-UHFFFAOYSA-N

Description générale

Lipase substrate (1,2-Di-O-lauryl-rac-glycero-3-(glutaric,acid 6-methylresorufin) ester, DGGR) is a chromogenic substrate for lipases. It is used in colorimetric methods to measure lipase activity. This substrate produces a red-purple compound, methylresorufin, upon digestion by the lipase enzyme.

Application

Lipase Substrate is used as substrate in a high‑throughput screening assay to measure the lipase activity in response to lipstatin production

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)

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Sigma-Aldrich

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Non-linearity within the primary measurement range of a lipase assay (<300 U/L) has been shown on Cobas® Roche analyzers, causing gaps in results distribution between 300 and 400 U/L. Since, new lipase method applications (LMAs) have been used. The purpose is to
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