113R-2

CD13 (EP117) Rabbit Monoclonal Primary Antibody

• Synonyme(s) : Aminopeptidase-N
• Code UNSPSC : 12352203

Propriétés

• Source biologique: rabbit
• Niveau de qualité: 100; 500
• Conjugué: unconjugated
• Forme d'anticorps: culture supernatant
• Type de produit anticorps: primary antibodies
• Clone: EP117, monoclonal
• Description: For In Vitro Diagnostic Use in Select Regions (See Chart)
• Forme: buffered aqueous solution
• Espèces réactives: human
• Conditionnement: vial of 0.1 mL concentrate (113R-24); vial of 0.1 mL concentrate Research Use Only (113R-24-RUO); vial of 0.5 mL concentrate (113R-25); vial of 1.0 mL concentrate (113R-26); vial of 1.0 mL concentrate Research Use Only (113R-26-RUO); vial of 1.0 mL pre-dilute Research Use Only (113R-27-RUO); vial of 1.0 mL pre-dilute ready-to-use (113R-27); vial of 7.0 mL pre-dilute ready-to-use (113R-28); vial of 7.0 mL pre-dilute ready-to-use Research Use Only (113R-28-RUO)
• Fabricant/nom de marque: Cell Marque^™
• Concentration: 0.1-5 μg/mL (predilute); 2.5-125 μg/mL (concentrate)
• Technique(s): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100 (concentrated)
• Isotype: IgG
• Contrôle: liver
• Conditions d'expédition: wet ice
• Température de stockage: 2-8°C
• Visualisation: cytoplasmic, membranous
• Informations sur le gène: human ... ANPEP(290)

Description

Description générale

CD13 (aminopeptidase-N) is a transmembrane protease present in many tissues and cell types (e.g., endothelial and epithelial cells, fibroblasts, and leukocytes). CD13 is expressed in various solid and hematological malignancies in humans and is useful in identifying acute myeloid leukemia when used in a panel including antibodies against CD13(+), CD34(+), CD117(+), CD16(-), and CD33(+). This protein is also expressed in myeloid sarcoma and anti-CD13 is useful in its identification using a panel.

In addition, it has been reported that CD13 is expressed in both normal and neoplastic liver tissue, where it exhibits a canalicular distribution pattern similar to that seen for polyclonal CEA and CD10. Thus, anti-CD13 can be useful as an additional marker in differentiating between HCC and non-hepatocellular neoplasms.

Qualité

United States - IVD
Canada - IVD
European Union - IVD
Japan - RUO

Liaison

CD13 Positive Control Slides, Product No. 113S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Forme physique

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Notes préparatoires

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Autres remarques

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Informations légales

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Code de la classe de stockage: 12 - Non Combustible Liquids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable