T2695

Tetrandrine

analytical standard, for drug analysis

• Synonyme(s) : (1β)-6,6′,7,12-Tetramethoxy-2,2′-dimethylberbaman
• Formule empirique (notation de Hill): C₃₈H₄₂N₂O₆
• Numéro CAS: 518-34-3
• Poids moléculaire : 622.75
• Numéro MDL: MFCD08689909
• Code UNSPSC : 41116107
• ID de substance PubChem : 329826723
• Nomenclature NACRES : NA.24

Propriétés

• Qualité: analytical standard, for drug analysis
• Niveau de qualité: 100
• Essai: ≥90%
• Forme: solid
• Technique(s): HPLC: suitable; gas chromatography (GC): suitable
• Application(s): forensics and toxicology; pharmaceutical (small molecule); veterinary
• Format: neat
• Chaîne SMILES: COc1ccc2C[C@@H]3N(C)CCc4cc(OC)c(OC)c(Oc5cc6[C@H](Cc7ccc(Oc1c2)cc7)N(C)CCc6cc5OC)c34
• InChI: 1S/C38H42N2O6/c1-39-15-13-25-20-32(42-4)34-22-28(25)29(39)17-23-7-10-27(11-8-23)45-33-19-24(9-12-31(33)41-3)18-30-36-26(14-16-40(30)2)21-35(43-5)37(44-6)38(36)46-34/h7-12,19-22,29-30H,13-18H2,1-6H3/t29-,30-/m0/s1
• Clé InChI: WVTKBKWTSCPRNU-KYJUHHDHSA-N

Description

Description générale

Tetrandrine (TET) is classified under the bisbenzylisoquinoline alkaloid family of compounds extracted from Stephania tetrandra S. Moore.

Application

Analgesic, antipyretic.
TET may be used as an analytical reference standard for the determination of TET in:

• Blood samples by online multidimensional solid phase extraction liquid chromatography coupled to tandem mass spectrometry (MD-SPE-LC-MS/MS) equipped with electrospray ionization (ESI) source and multiple reaction monitoring (MRM) detection.
• Rat plasma by ultra-high performance liquid chromatography (UHPLC) combined with MS/MS with MRM detection.
• Qi-Fang-Xi-Bi-Granules used in Chinese medicine by reversed phase HPLC equipped with ultraviolet (UV) detector.
• Fangji Huangqi Tang Chinese medicine by UHPLC coupled to triple quadrupole mass spectrometry (QqQ-MS) with MRM detection.

It may be used as an internal standard for the determination of hernandezine in:

• Rat plasma and tissues by UHPLC-MS/MS with MRM detection.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Informations sur la sécurité

• Pictogrammes: GHS06
• Mention d'avertissement: Danger
• Mentions de danger: H300
• Conseils de prudence: P264 - P270 - P301 + P310 - P405 - P501
• Classification des risques: Acute Tox. 2 Oral
• Code de la classe de stockage: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)