437573

N,N-Diméthylformamide

ACS reagent, ≥99.8%

• Synonyme(s) : DMF, NSC 5356
• Formule linéaire : HCON(CH₃)₂
• Numéro CAS: 68-12-2
• Poids moléculaire : 73.09
• Beilstein: 605365
• Numéro CE : 200-679-5
• Numéro MDL: MFCD00003284
• Code UNSPSC : 12352111
• ID de substance PubChem : 24867382
• Qualité: ACS reagent
• Essai: ≥99.8%
• Technique(s): electrophoresis: suitable
• pb: 153 °C (lit.)
• Pression de vapeur: 2.7 mmHg ( 20 °C)

Propriétés

• Qualité: ACS reagent
• Niveau de qualité: 200
• Densité de vapeur: 2.5 (vs air)
• Pression de vapeur: 2.7 mmHg ( 20 °C)
• Essai: ≥99.8%
• Forme: liquid
• Température d'inflammation spontanée: 833 °F
• Limite d'explosivité: 15.2 %
• Technique(s): electrophoresis: suitable
• Impuretés: ≤0.0005 meq/g Titr. acid; ≤0.003 meq/g Titr. base; ≤0.15% water
• Résidus d'évap.: ≤0.005%
• Couleur: APHA: ≤15
• Indice de réfraction: n20/D 1.430 (lit.)
• pH: 6.7
• pb: 153 °C (lit.)
• Pf: −61 °C (lit.)
• Solubilité: water: miscible
• Densité: 0.944 g/mL (lit.)
• Chaîne SMILES: [H]C(=O)N(C)C
• InChI: 1S/C3H7NO/c1-4(2)3-5/h3H,1-2H3
• Clé InChI: ZMXDDKWLCZADIW-UHFFFAOYSA-N

Description

Description générale

N,N-Dimethylformamide (DMF) is a polar organic solvent with a wide range of industrial applications. It is a precursor for numerous reactions such as formylation, aminocarbonylation, amination, amidation and cyanation. Along with phosphorus oxychloride, it forms Vilsmeier reagent used in the formylation of reactive aromatic and heteroaromatic substrates. Dielectric relaxation experiments on DMF have been conducted between 238.15K and 338.15K. The thermophysical properties of the molecular interactions between DMF and the ionic liquids, ammonium salts and imidazolium salts have been studied. The characteristics of solute-solvent interactions between ammonium nitrate and DMF have been investigated.

Application

N,N-Dimethylformamide (DMF) may be used in the following processes:

• As a solvent synthesis of gold nanoparticles.
• As a solvent in capillary electrophoresis.
• Regioselective synthesis of N,N-dimethylaminopyridzines by reacting with choropyridazines.
• Synthesis of urea-N,N-dimethylformamide, a 3:1 solvate with urea.

Solvant pour de nombreux composés organiques hydrophobes

Informations sur la sécurité

• Pictogrammes: GHS02,GHS08,GHS07
• Mention d'avertissement: Danger
• Mentions de danger: H226,H312 + H332,H319,H360D
• Conseils de prudence: P210 - P280 - P303 + P361 + P353 - P304 + P340 + P312 - P305 + P351 + P338 - P308 + P313
• Classification des risques: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Eye Irrit. 2 - Flam. Liq. 3 - Repr. 1B
• Code de la classe de stockage: 3 - Flammable liquids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): 135.5 °F - closed cup
• Point d'éclair (°C): 57.5 °C - closed cup
• Équipement de protection individuelle: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter