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199737

Sigma-Aldrich

New Coccine

Dye content 75 %

Synonyme(s) :

Acid Red 18, Ponceau 4 R

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About This Item

Formule empirique (notation de Hill):
C20H11N2Na3O10S3
Numéro CAS:
2611-82-7
Poids moléculaire :
604.47
Numéro C.I. (Colour Index):
16255
Numéro Beilstein :
4122340
Numéro CE :
220-036-2
Numéro MDL:
MFCD00004084
Code UNSPSC :
12171500
ID de substance PubChem :
24851935
Nomenclature NACRES :
NA.47

Forme

powder

Niveau de qualité

200

Composition

Dye content, 75%

Solubilité

water: 1 mg/mL, clear

λmax

350 nm (2nd)
506 nm

Application(s)

diagnostic assay manufacturing
hematology
histology

Température de stockage

room temp

Chaîne SMILES 

[Na+].[Na+].[Na+].Oc1ccc2cc(cc(c2c1\N=N\c3ccc(c4ccccc34)S([O-])(=O)=O)S([O-])(=O)=O)S([O-])(=O)=O

InChI

1S/C20H14N2O10S3.3Na/c23-16-7-5-11-9-12(33(24,25)26)10-18(35(30,31)32)19(11)20(16)22-21-15-6-8-17(34(27,28)29)14-4-2-1-3-13(14)15;;;/h1-10,23H,(H,24,25,26)(H,27,28,29)(H,30,31,32);;;/q;3*+1/p-3/b22-21+;;;

Clé InChI

SWGJCIMEBVHMTA-ZRUFZDNISA-K

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Application

New Coccine has been used to determine its decolorization by fungi Phanerochaete chrysosporium and Pleurotus sajorcaju.

Actions biochimiques/physiologiques

New Coccine also referred to as ponceau 4 R, is a synthetic red tar dye. It belongs to the group of azo dyes. New Coccine is extensively used as a food colorant. When the intact dye reaches the intestine, it cause colon specific DNA damage in mice.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)

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Certificats d'analyse (COA)

Lot/Batch Number
SHBL8447
SHBL0647
MKCF1096
MKBX7221V
MKBT7388V

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DNA Damage Induced by Red Food Dyes Orally Administered to Pregnant and Male Mice
Tsuda S
Toxicological Sciences, 61, 92-99 (2001)
Differential colon DNA damage induced by azo food additives between rats and mice
Shimada C
The Journal of Toxicological Sciences, 35, 547-554 (2010)
Yunfei Xie et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 96, 600-604 (2012-08-08)
Ponceau 4R is used as a coloring agent in many different products, such as food, drinks, medicines, cosmetics and tobacco. However, ponceau 4R also shows carcinogenic, teratogenic and mutagenic behavior in high doses. In this work, standard Raman, theoretical Raman
Saeed Shahrokhian et al.
Bioelectrochemistry (Amsterdam, Netherlands), 90, 36-43 (2012-11-28)
The electrooxidation of clozapine (CLZ) was studied on the surface of a glassy carbon electrode (GCE) modified with a thin film of multiwalled carbon nanotubes (MWCNTs)/new coccine (NC) doped polypyrrole (PPY) by using linear sweep voltammetry (LSV). The pH of
C H Weng et al.
Water science and technology : a journal of the International Association on Water Pollution Research, 44(10), 279-284 (2002-01-17)
The adsorption characteristics of an anionic azo dye (new coccine) onto digested sludge have been studied. Results show that the dye can effectively be removed by sludge. It was found that the adsorption rate is very rapid and the equilibrium
Afficher tous les articles scientifiques apparentés

Protocoles

HPLC Analysis of Synthetic Food Dyes on Ascentis® Express C18

Separation of Tartrazine; Amaranth; Indigo carmine; New Coccine; Sunset Yellow FCF; Allura Red AC; Fast Green FCF; Erioglaucine disodium salt; Erythrosin B sodium salt; Phloxine B; Rose bengal

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