FCMAB203P

Milli-Mark^® Anti-CD64-PE Antibody, clone 10.1

clone 10.1, Milli-Mark^®, from mouse

• Synonyme(s) : High affinity immunoglobulin gamma Fc receptor I, IgG Fc receptor I, Fc-gamma RIA, FcgammaRIa, Fc-gamma RI, FcRI
• Code UNSPSC : 12352203
• eCl@ss : 32160702
• Nomenclature NACRES : NA.44

Propriétés

• Source biologique: mouse
• Niveau de qualité: 100
• Conjugué: PE
• Forme d'anticorps: purified immunoglobulin
• Type de produit anticorps: primary antibodies
• Clone: 10.1, monoclonal
• Espèces réactives: human
• Fabricant/nom de marque: Milli-Mark^®
• Technique(s): flow cytometry: suitable
• Isotype: IgG1κ
• Numéro d'accès NCBI: NP_000034.1
• Numéro d'accès UniProt: P12314
• Conditions d'expédition: wet ice
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... FCGR1A(2209)

Description

Description générale

CD64 is the high-affinity IgG Fc receptor belonging to the immunoglobulin supergene family (Guyre, 2002). CD64 is a 72 kDa glycoprotein which binds monomeric IgG (human IgG>>IgG>>>IgG4>>>IgG2 and mouse IgG3>IgG2a>>>IgG1, IgG2b). Three genes: FcγR1A, FcγR1B and FcγR1C, which have >98 percent identity at the nucleotide level, have been identified and mapped to chromosome 1, band q21.1 (Sun,1997)). The FcγR1A gene, which specified the high-affinity IgG receptor, encodes three C2-type Ig-like extracellular domains, a 21 amino acid transmembrane region, and a charge cytoplasmic tail of 61 amino acids (Sun, 1997)(van de Winkel,1993).

Spécificité

Antibody recognizes Human CD64 antigen.

Immunogène

Human rheumatoid synovial fluid cells and monocytes.

Application

Milli-Mark Anti-CD64-PE Antibody, clone 10.1 detects level of CD64 & has been published & validated for use in FC.

Research Category
Inflammation & Immunology

Research Sub Category
Immunoglobulins & Immunology

Qualité

Evaluated by flow cytometry using human PBMCs

Description de la cible

72 kDa (Sun W, 1997)

Forme physique

Protein A purified

Purified Mouse monoclonal IgG1 conjugated to PE in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2.

Stockage et stabilité

Maintained refrigerated at 2-8°C from date of receipt. Protected from light in undiluted aliquots for 6 months from date of receipt.

Remarque sur l'analyse

Control
PBMC′s

Autres remarques

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Informations légales

MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 12 - Non Combustible Liquids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable