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Principaux documents

AB5986

Sigma-Aldrich

Anti-Tyrosine Hydroxylase Antibody

CHEMICON®, rabbit polyclonal

Synonyme(s) :

TH, Tyrosine Monooxygenase

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About This Item

Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41

product name

Anti-Tyrosine Hydroxylase Antibody, serum, Chemicon®

Source biologique

rabbit

Niveau de qualité

Forme d'anticorps

serum

Type de produit anticorps

primary antibodies

Clone

polyclonal

Espèces réactives

rat

Fabricant/nom de marque

Chemicon®

Technique(s)

immunohistochemistry: suitable

Numéro d'accès UniProt

Conditions d'expédition

dry ice

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

rat ... Th(25085)

Spécificité

Tyrosine Hydroxylase. Immunohistochemical distribution throughout the brain shows that staining is restricted to those neurons known to contain the enzyme. The antibody has proven useful in staining catecholaminergic neurons. AB5986 stains these neurons intensely, including dendritic processes and fine nerve terminals.

Immunogène

Synthetic peptide corresponding to amino acids 32-47 of rat Tyrosine Hydroxylase.

Application

Immunohistochemistry: 1:2,000-1:4,000.

Optimal working dilutions must be determined by end user.
Research Category
Neuroscience
Research Sub Category
Neurotransmitters & Receptors

Neuronal & Glial Markers
This Anti-Tyrosine Hydroxylase Antibody is validated for use in IH for the detection of Tyrosine Hydroxylase.

Forme physique

Rabbit serum. Lyophilized. Reconstitute with 50 μL of sterile distilled water. Centrifuge to remove any insoluble material. Contains no preservative.

Stockage et stabilité

Maintain lyophilized material frozen at -20°C to -70°C for up to 12 months. After reconstitution maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles. Glycerol (1:1, ACS or better grade) can be added for additional stability.

Remarque sur l'analyse

Control
POSITIVE CONTROL: brain (sympathetic nerve terminals) and adrenal glands.

Informations légales

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

Ovarian expression of alpha (1)- and beta (2)-adrenoceptors and p75 neurotrophin receptors in rats with steroid-induced polycystic ovaries.
Luigi Manni, Agneta Holmang, Thomas Lundeberg, Luigi Aloe, Elisabet Stener-Victorin et al.
Autonomic Neuroscience : Basic & Clinical null
Effect of anti-NGF on ovarian expression of alpha1- and beta2-adrenoceptors, TrkA, p75NTR, and tyrosine hydroxylase in rats with steroid-induced polycystic ovaries.
Manni, L; Holmang, A; Cajander, S; Lundeberg, T; Aloe, L; Stener-Victorin, E
American Journal of Physiology. Regulatory, Integrative and Comparative Physiology null
S M Miller et al.
Neuroscience, 159(4), 1384-1396 (2009-05-05)
Dopamine receptor activity in the rodent medial preoptic area (mPOA) is crucial for the display of maternal behaviors, as well as numerous other physiological and behavioral functions. However, the origin of dopaminergic input to the mPOA has not been identified
Antibodies to a segment of tyrosine hydroxylase phosphorylated at serine 40.
Goldstein, M, et al.
Journal of Neurochemistry, 64, 2281-2287 (1995)
Antibodies to a synthetic peptide corresponding to a Ser-40-containing segment of tyrosine hydroxylase: activation and immunohistochemical localization of tyrosine hydroxylase.
Lee, K Y, et al.
Journal of Neurochemistry, 53, 1238-1244 (1989)

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