8.07066

Oxalyl chloride

for synthesis

• Synonyme(s) : Oxalyl chloride, Oxalic acid dichloride
• Formule empirique (notation de Hill): C₂Cl₂O₂
• Numéro CAS: 79-37-8
• Poids moléculaire : 126.93
• Numéro MDL: MFCD00000704
• Code UNSPSC : 12352106
• Numéro de classement CE : 201-200-2
• Nomenclature NACRES : NA.22

Propriétés

• Pression de vapeur: 200 hPa ( 20 °C)
• Niveau de qualité: 200
• Forme: liquid
• Point d'ébullition: 63-64 °C/1013 hPa
• Pf: -12 °C
• Température de transition: flash point >100 °C
• Densité: 1.48 g/cm³ at 20 °C
• Température de stockage: 2-30°C
• InChI: 1S/C2Cl2O2/c3-1(5)2(4)6
• Clé InChI: CTSLXHKWHWQRSH-UHFFFAOYSA-N

Description

Application

• Mild deprotection of the N-tert-butyloxycarbonyl (N-Boc) group using oxalyl chloride: This study explores the mild deprotection capabilities of oxalyl chloride on N-Boc substrates, offering a potential method for sensitive chemical syntheses (N George, S Ofori, S Parkin, SG Awuah, 2020).
• Nickel-Catalyzed Highly Selective Reductive Carbonylation Using Oxalyl Chloride as the Carbonyl Source: Demonstrates the use of oxalyl chloride as an effective carbonyl source in nickel-catalyzed reductive carbonylation, highlighting its utility in organic synthesis (J Wang, Y Yin, X He, QL Duan, R Bai, HW Shi, 2023).
• A novel and highly efficient esterification process using triphenylphosphine oxide with oxalyl chloride: Introduces a novel esterification process utilizing oxalyl chloride and triphenylphosphine oxide, which improves reaction efficiency and product yield in organic chemistry (M Jia, L Jiang, F Niu, Y Zhang, 2018).
• Dimethyl sulfoxide/oxalyl chloride: A useful reagent for sulfenyletherification: Discusses the use of a dimethyl sulfoxide/oxalyl chloride mixture in sulfenyletherification reactions, providing insights into advanced synthesis techniques for sulfur-containing compounds (Y Gao, S Cheng, T Zhang, R Ding, Y Liu, 2018).

Remarque sur l'analyse

Assay (argentometric): ≥ 98.0 %
Identity (IR): passes test
A slight precipitate of oxalic acid is normal and does not affect the specified quality of the product.

Informations sur la sécurité

• Pictogrammes: GHS02,GHS05,GHS06
• Mention d'avertissement: Danger
• Mentions de danger: H260 - H301 + H331 - H314
• Conseils de prudence: P223 - P231 + P232 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Classification des risques: Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Eye Dam. 1 - Skin Corr. 1B - Water-react 1
• Risques supp: EUH014 - EUH029 - EUH071
• Code de la classe de stockage: 4.3 - Hazardous materials, which set free flammable gases upon contact with water
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable