317210

DM-NITROPHEN Reagent, Tetrasodium Salt

Caged Ca2+ chelator that undergoes a major and rapid decrease in Ca2+-binding affinity upon photolysis.

• Synonyme(s) : DM-NITROPHEN Reagent, Tetrasodium Salt, 1-(2-Nitro-4,5-dimethoxyphenyl)-1,2-diaminoethane-N,N,Nʹ,Nʹ-tetraacetic Acid, 4Na, Dimethoxynitrophenamine, 4Na
• Formule empirique (notation de Hill): C₁₈H₁₉N₃O₁₂ · 4Na
• Poids moléculaire : 561.32
• Code UNSPSC : 12352200

Propriétés

• Niveau de qualité: 100
• Pureté: ≥93% (HPLC)
• Forme: solid
• Pertinence de la réaction: reagent type: chelator
• Fabricant/nom de marque: Calbiochem^®
• Conditions de stockage: OK to freeze; desiccated (hygroscopic); protect from light
• Couleur: orange
• Solubilité: water: 100 mg/mL
• Conditions d'expédition: wet ice
• Température de stockage: −20°C

Description

Description générale

Caged Ca²⁺ chelator that undergoes a major and rapid decrease in Ca²⁺-binding affinity upon photolysis. Can be microinjected or permeabilized into cells. May also be useful as a caged Mg²⁺ chelator. K_d (Ca²⁺) = 5 nM; K_d (Mg²⁺) = 2-5 µM.

Caged Ca²⁺ chelator that undergoes a major and rapid decrease in Ca²⁺-binding affinity upon photolysis. Can be microinjected or used with permeabilized cells. May also be useful as caged Mg²⁺ chelator. K_d (Ca²⁺) = 5 nM; K_d (Mg²⁺) = 2-5 µM.

Avertissement

Toxicity: Standard Handling (A)

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Autres remarques

Mulkey, R.M., and Zucker, R.S. 1993. J. Physiol. 462, 243.
Zucker, R.S. 1993. Cell Calcium 14, 87.
McCray, J.A., et al. 1992. Biochemistry31, 8856.
Delaney, K.R., and Zucker, R.S. 1990. J. Physiol.426, 473.
Kaplan, J.H., and Ellis-Davies, G.C. 1988. Proc. Natl. Acad. Sci. USA85, 6571.
Morad, M., et al. 1988. Science241, 842.

Informations légales

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable