850457P

16:0-18:1 PC

Avanti Polar Lipids

• Synonyme(s) : 1-hexadecanoyl-2--(9Z-octadecenoyl)-sn-glycero-3-phosphocholine; POPC; PC(16:0/18:1(9Z))
• Formule empirique (notation de Hill): C₄₂H₈₂NO₈P
• Numéro CAS: 26853-31-6
• Poids moléculaire : 760.08
• Code UNSPSC : 51191904
• Nomenclature NACRES : NA.25

Propriétés

• Description: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine
• Pureté: >99% (TLC)
• Forme: powder
• Conditionnement: pkg of 1 × 1 g (850457P-1g); pkg of 2 × 100 mg (850457P-200mg); pkg of 5 × 100 mg (850457P-500mg); pkg of 1 × 25 mg (850457P-25mg)
• Fabricant/nom de marque: Avanti Polar Lipids
• Type de lipide: phospholipids; cardiolipins
• Conditions d'expédition: dry ice
• Température de stockage: −20°C
• Chaîne SMILES: [O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O)=O
• InChI: 1S/C42H82NO8P/c1-6-8-10-12-14-16-18-20-21-23-25-27-29-31-33-35-42(45)51-40(39-50-52(46,47)49-37-36-43(3,4)5)38-48-41(44)34-32-30-28-26-24-22-19-17-15-13-11-9-7-2/h20-21,40H,6-19,22-39H2,1-5H3/b21-20-/t40-/m1/s1
• Clé InChI: WTJKGGKOPKCXLL-VYOBOKEXSA-N

Description

Description générale

POPC is typically considered one of the model lipids for biophysical experiments. The fatty acid composition, i.e., saturated chain in the sn-1 position and unsaturated chain in the sn-2 position, mimics mammalian phospholipid composition. Since the major constituent in Egg PC is 1-palmitoyl-2-oleoyl PC, POPC is an excellent synthetic substitute for EPC.

Application

16:0-18:1 PC has been used in the preparation of liposomes for the muramyl tripeptide encapsulation. It has also been used in the preparation of membrane scaffold protein 1 nanodisc. 16:0-18:1 PC may be used in the synthesis of discoidal reconstituted high-density lipoproteins.

Actions biochimiques/physiologiques

1-palmitoyl-2-oleoyl-glycero-3-phosphocholine (POPC)or 16:0-18:1 PC plays an important role as a lung surfactant and reduces surface tension. POPC mimics natural cell membrane and may be useful for unsaturated lipids oxidation studies. Its interaction with ozone leads to oxidative decomposition at the oleoyl strand C-C moiety.

Conditionnement

5 mL Clear Glass Sealed Ampule (850457P-200mg)

5 mL Clear Glass Sealed Ampule (850457P-25mg)

5 mL Clear Glass Sealed Ampule (850457P-500mg)

60 mL Amber Wide Mouth Screw Cap Glass Bottle (850457P-1g)

Informations légales

Avanti Research is a trademark of Avanti Polar Lipids, LLC