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Key Documents

850356P

Avanti

4ME 16:0 PC

Avanti Research - A Croda Brand

Synonyme(s) :

1,2-Diphytanoyl-3-sn-phosphatidylcholine, 1,2-di-(3,7,11,15-tetramethylhexadecanoyl)-sn-glycero-3-phosphocholine; PC(16:0(3me,7me,11me,15me)/16:0(3me,7me,11me,15me)), DPhPC, Diphytanoylphosphatidylcholine

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About This Item

Formule empirique (notation de Hill):
C48H96NO8P
Numéro CAS:
Poids moléculaire :
846.25
Code UNSPSC :
51191904
Nomenclature NACRES :
NA.25

Description

1,2-diphytanoyl-sn-glycero-3-phosphocholine

Pureté

>99% (TLC)

Forme

powder

Conditionnement

pkg of 1 × 200 mg ((850356P-200MG))
pkg of 1 × 25 mg ((850356P-25MG))
pkg of 1 × 500 mg ((850356P-500MG))

Fabricant/nom de marque

Avanti Research - A Croda Brand

Conditions d'expédition

dry ice

Température de stockage

−20°C

Chaîne SMILES 

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CC(C)CCCC(C)CCCC(C)CCCC(C)C)=O)COC(CC(C)CCCC(C)CCCC(C)CCCC(C)C)=O)=O

Description générale

Lipids containing diphytanoyl fatty acid chains have been used to produce stable planar lipid membranes (see References). Diphytanoyl phosphatidylcholine does not exhibit a detectable gel to liquid crystalline phase transition from -120°C to +120°C.The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products from oxidization and hydrolysis.

Application

4ME 16:0 PC has been used:
  • in the electrophysiology studies of chloride channel
  • for the generation of Droplet-Hydrogel Bilayer (DHB), which is used for protein reconstitution studies
  • for the generation of lipid bilayers for single channel and ion selectivity measurements studies

Actions biochimiques/physiologiques

1,2-diphytanoyl-sn-glycero-3-phosphocholine (4ME 16:0 PC) or DPhPC has choline head groups and favors formation of membrane lipid bilayer. It displays low permeability towards ions and water. DPhPC is majorly used lipid for electrophysiological measurements and ion conductivity studies.

Conditionnement

20 mL Clear Glass Screw Cap Vial (850356P-200mg)
30 mL Amber Wide Mouth Bottle with Screw Cap (850356P-500mg)
5 mL Clear Glass Sealed Ampule (850356P-25mg)

Informations légales

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3


Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Unusual Constriction Zones in the Major Porins OmpU and OmpT from Vibrio cholerae
Pathania M, et al.
Structure, 26(5), 708-721 (2018)
Physical properties of bilayer membranes formed from a synthetic saturated phospholipid in n-decane.
W R Redwood et al.
Biochimica et biophysica acta, 233(1), 1-6 (1971-03-09)
Chan Cao et al.
Nature communications, 10(1), 4918-4918 (2019-10-31)
Nanopore sensing is a powerful single-molecule approach for the detection of biomolecules. Recent studies have demonstrated that aerolysin is a promising candidate to improve the accuracy of DNA sequencing and to develop novel single-molecule proteomic strategies. However, the structure-function relationship
Stephanie Tristram-Nagle et al.
Chemistry and physics of lipids, 163(6), 630-637 (2010-05-08)
Diphytanoylphosphatidylcholine (DPhyPC) is a branched chain lipid often used for model membrane studies, including peptide/lipid interactions, ion channels and lipid rafts. This work reports results of volume measurements, water permeability measurements P(f), X-ray scattering from oriented samples, and X-ray and
Tim Diederichs et al.
Nature communications, 10(1), 5018-5018 (2019-11-07)
Nanopores are key in portable sequencing and research given their ability to transport elongated DNA or small bioactive molecules through narrow transmembrane channels. Transport of folded proteins could lead to similar scientific and technological benefits. Yet this has not been

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