810176C

18:1-12:0 NBD PA

Avanti Polar Lipids 810176C

• Synonyme(s) : 1-oleoyl-2-{12-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl}-sn-glycero-3-phosphate (ammonium salt)
• Formule empirique (notation de Hill): C₃₉H₆₈N₅O₁₁P
• Numéro CAS: 384833-04-9
• Poids moléculaire : 813.96
• Code UNSPSC : 12352211
• Nomenclature NACRES : NA.25

Propriétés

• Pureté: >99% (TLC)
• Forme: liquid
• Conditionnement: pkg of 1 × 1 mL (810176C-1mg)
• Fabricant/nom de marque: Avanti Polar Lipids 810176C
• Concentration: 1 mg/mL (810176C-1mg)
• Conditions d'expédition: dry ice
• Température de stockage: −20°C

Description

Description générale

Phosphatidic acid (PA) is a simple anionic membrane phospholipid. The amphipathic phospholipid contains a polar head group and two long hydrophobic acyl chains. NBD PA is a fluorescent probe containing 7-nitrobenz-2-oxa-1,3-diazol-4-yl (NBD) linked to the sn-2 fatty acid of PA.

Application

18:1-12:0 NBD PA or 1-oleoyl-2-{12-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl}-sn-glycero-3-phosphate (ammonium salt) has been used in donor liposomes for phosphatidic acid (PA) transfer activity assay. It might be used:in the preparation of PA small unilamellar vesicles (SUVs) to determine mammalian target of rapamycin complex 1 (mTORC1) lysosomal translocation. It may be used in NBD-PA and NBD phosphatidyl choline uptake assays and to measure lipid transfer specificity of Ups1 mutants

Actions biochimiques/physiologiques

Phosphatidic acid (PA) is crucial for intracellular signaling involved in various cellular processes, including membrane trafficking and sperm hyper-activation. PA reacts with water and other phospholipids to produce lipid bilayers and multicomponent bilayers, respectively.

Conditionnement

5 mL Amber Glass Screw Cap Vial (810176C-1mg)

Informations légales

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Informations sur la sécurité

• Pictogrammes: GHS06,GHS08
• Mention d'avertissement: Danger
• Mentions de danger: H302 - H315 - H319 - H331 - H336 - H351 - H361d - H372 - H412
• Conseils de prudence: P201 - P273 - P301 + P312 + P330 - P302 + P352 - P304 + P340 + P311 - P308 + P313
• Classification des risques: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
• Organes cibles: Central nervous system
• Code de la classe de stockage: 6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): does not flash
• Point d'éclair (°C): does not flash