205249

Di-tert-butyl dicarbonate

99%, for peptide synthesis, ReagentPlus^®

• Synonyme(s) : Boc anhydride, Di-tert-butyl pyrocarbonate
• Formule linéaire : [(CH₃)₃COCO]₂O
• Numéro CAS: 24424-99-5
• Poids moléculaire : 218.25
• Numéro Beilstein : 1911173
• Numéro CE : 246-240-1
• Numéro MDL: MFCD00008805
• Code UNSPSC : 12352302
• ID de substance PubChem : 24852315
• Nomenclature NACRES : NA.22

Propriétés

• product name: Di-tert-butyl dicarbonate, ReagentPlus^®, 99%
• Niveau de qualité: 200
• Gamme de produits: ReagentPlus^®
• Pureté: 99%
• Forme: solid or liquid
• Indice de réfraction: n20/D 1.409 (lit.)
• Point d'ébullition: 56-57 °C/0.5 mmHg (lit.)
• Pf: 23 °C (lit.)
• Densité: 0.95 g/mL at 25 °C (lit.)
• Application(s): peptide synthesis
• Température de stockage: 2-8°C
• Chaîne SMILES: CC(C)(C)OC(=O)OC(=O)OC(C)(C)C
• InChI: 1S/C10H18O5/c1-9(2,3)14-7(11)13-8(12)15-10(4,5)6/h1-6H3
• Clé InChI: DYHSDKLCOJIUFX-UHFFFAOYSA-N

Description

Application

Aminomethyl allene was prepared by reaction of Boc propargyl amine with formaldehyde, diisopropylamine and copper bromide as part of a series of Bovine Plasma Amine Oxidase inactivators.

Protection of alcohols as Boc derivatives via Lewis acid catalysis.

Reagent for the introduction of the Boc protecting group.

Reagent for the preparation of Boc protected amines.

Tris-Boc protected hydrazine allows preparation of Fmoc ester in a chromophoric reagent to monitor solid-phase aldehydes.

Automated Boc protection and deprotection can be done using Synple Automated Synthesis Platform (SYNPLE-SC002), Boc protection cartridges ((SYNPLE-B001), (SYNPLE-B002), and Boc deprotection cartridges (SYNPLE-B011)

Avertissement

Hydrolyzes to t-butanol and CO₂; causes internal pressure in bottle if exposed to moisture.

Informations légales

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Pictogrammes: GHS02,GHS06,GHS05
• Mention d'avertissement: Danger
• Mentions de danger: H226,H315,H317,H318,H330,H335
• Conseils de prudence: P210 - P233 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Classification des risques: Acute Tox. 1 Inhalation - Eye Dam. 1 - Flam. Liq. 3 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
• Organes cibles: Respiratory system
• Code de la classe de stockage: 3 - Flammable liquids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): 98.6 °F - closed cup
• Point d'éclair (°C): 37 °C - closed cup
• Équipement de protection individuelle: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter