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GRM3

glutamate receptor, metabotropic 3

Synonymes:
GLUR3, GPRC1C, MGLUR3, mGlu3
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(2913) Summary: L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. [provided by RefSeq, Jul 2008]
  • Mouse(108069) glutamate receptor, metabotropic 3
  • Rat(24416) glutamate receptor, metabotropic 3
  • Zebrafish(565256) glutamate receptor, metabotropic 3
  • dog(100683236) glutamate receptor, metabotropic 3
  • domestic cat(101095810) glutamate receptor, metabotropic 3
  • cow(541056) glutamate receptor, metabotropic 3
  • Horse(100049918) glutamate receptor, metabotropic 3
  • chicken(418644) glutamate receptor, metabotropic 3
  • domestic guinea pig(100731837) glutamate receptor, metabotropic 3
  • naked mole-rat(101713039) glutamate receptor, metabotropic 3
  • sheep(101113057) glutamate receptor, metabotropic 3

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Small Molecule - Agonist

Référence du produit
Description
Espèce(s)
trans-(±)-ACPD monohydrate, solid, ≥97% (NMR),
Espèce(s)
human
L-(+)-2-Amino-4-phosphonobutyric acid, optical purity optical purity: ≥95% (HPLC, Marfey′s reagent),
Espèce(s)
rat, human
L-Glutamic acid, ReagentPlus®, ≥99% (HPLC),
Espèce(s)
rat, human
L-Glutamic acid, from non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-100.5%,
Espèce(s)
rat, human
L-Glutamic acid, BioUltra, ≥99.5% (NT),
Espèce(s)
rat, human

Small Molecule - Antagonist

Référence du produit
Description
Espèce(s)
DL-2-Amino-3-phosphonopropionic acid, ,
Espèce(s)
human
L-Glutamic acid, ReagentPlus®, ≥99% (HPLC),
Espèce(s)
rat, human
L-Glutamic acid, from non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-100.5%,
Espèce(s)
rat, human
L-Glutamic acid, BioUltra, ≥99.5% (NT),
Espèce(s)
rat, human
L-Glutamic acid, FCC,
Espèce(s)
rat, human

Small Molecule - Mixed Agonist/Antagonist

Référence du produit
Description
Espèce(s)
L-(+)-2-Amino-4-phosphonobutyric acid, optical purity optical purity: ≥95% (HPLC, Marfey′s reagent),
Espèce(s)
rat, human
L-Glutamic acid, ReagentPlus®, ≥99% (HPLC),
Espèce(s)
rat, human
L-Glutamic acid, from non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-100.5%,
Espèce(s)
rat, human
L-Glutamic acid, BioUltra, ≥99.5% (NT),
Espèce(s)
rat, human
L-Glutamic acid, FCC,
Espèce(s)
rat, human

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human GRM3,
Espèce(s)
human