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Key Documents

SAB5300232

Sigma-Aldrich

Monoclonal Anti-NQO1 antibody produced in mouse

clone 4D12, ascites fluid

Synonym(s):

DHQU, DIA4, DTD, NMOR1, QR1

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

mouse

Quality Level

100

conjugate

unconjugated

antibody form

ascites fluid

antibody product type

primary antibodies

clone

4D12, monoclonal

mol wt

31 kDa

species reactivity

human

technique(s)

direct ELISA: 1:10,000
flow cytometry: 1:200-1:400
immunohistochemistry: 1:200-1:1,000
western blot: 1:500-1:2,000

isotype

IgG1

NCBI accession no.

NM_000903.2

UniProt accession no.

P15559

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... NQO1(1728)

Related Categories

Immunogen

Purified recombinant fragment of human NQO1 expressed in E.coli.
Mouse monoclonal antibody raised against NQO1

Physical form

Ascitic fluid containing 0.03% sodium azide.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Scott A Reisman et al.
Archives of dermatological research, 306(5), 447-454 (2013-12-24)
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Junichi Sasaki et al.
Bioorganic & medicinal chemistry, 22(21), 6039-6046 (2014-10-05)
quinone oxidoreductase 1 (NQO1) is an obligate two-electron reductase and is highly expressed in many human solid cancers. Because NQO1 can be induced immediately after exposure to ionizing radiation, we aimed to develop an NQO1-targeted radiolabeled agent to establish a
Yasunobu Matsuda et al.
International journal of clinical and experimental pathology, 7(5), 2032-2043 (2014-06-27)
Hepatitis B virus X (HBX) protein plays a crucial role in carcinogenesis, but its mechanism is unclear. The involvement of ataxia telangiectasia mutated (ATM) kinase in the enhanced redox system was investigated by examining the phosphorylation level of ATM in
Naoki Mine et al.
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CBP501 is an anticancer drug candidate that was investigated in two randomized phase II clinical trials for patients with nonsquamous non-small cell lung cancer (NSCLC) and malignant pleural mesothelioma (MPM). CBP501 has been shown to have two mechanisms of action

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