SAB4300628

Anti-phospho-CK2α (pThr³⁶⁰/Ser³⁶²) antibody produced in rabbit

affinity isolated antibody

• Synonym(s): Anti-CK2A1, Anti-CKII, Anti-CSNK2A1
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: ~42 kDa
• species reactivity: human, rat, mouse
• concentration: 1 mg/mL
• technique(s): western blot: 1:500-1:1000
• isotype: IgG
• immunogen sequence: (V-P-Tp-P-Sp-P-L)
• NCBI accession no.: NM_001903.2
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: phosphorylation (pThr360/pSer362)
• Gene Information: human ... CTNNA1(1495)

Description

General description

The antibody detects endogenous level of CK2 only when phosphorylated at thronine 360.

Immunogen

Peptide sequence around phosphorylation site of threonine360/serine 362 (V-P-Tp-P-Sp-P-L), according to the protein NP_001894.2

Features and Benefits

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Target description

Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. The alpha and alpha′ chains contain the catalytic site. Participates in Wnt signaling. CK2 phosphorylates ′Ser-392′ of p53/TP53 following UV irradiation.

Physical form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable