482R-1

p63 (EP174) Rabbit Monoclonal Primary Antibody

• UNSPSC Code: 12352203

Properties

• biological source: rabbit
• Quality Level: 100; 500
• conjugate: unconjugated
• antibody form: culture supernatant
• antibody product type: primary antibodies
• clone: EP174
• description: For In Vitro Diagnostic Use in Select Regions
• form: buffered aqueous solution
• species reactivity: human
• packaging: vial of 0.1 mL concentrate (482R-14); vial of 0.1 mL concentrate, Research Use Only (482R-14-RUO); vial of 0.5 mL concentrate (482R-15); vial of 1.0 mL concentrate (482R-16); vial of 1.0 mL concentrate, Research Use Only (482R-16-RUO); vial of 1.0 mL pre-dilute ready-to-use, Research Use Only (482R-17-RUO); vial of 1.0 mL pre-dilute, ready to use (482R-17); vial of 25.0 mL pre-dilute ready-to-use (482R-10); vial of 25.0 mL pre-dilute ready-to-use, Research Use Only (482R-10-RUO); vial of 7.0 mL pre-dilute, ready to use (482R-18); vial of 7.0 mL pre-dilute, ready to use, Research Use Only (482R-18-RUO)
• manufacturer/tradename: Cell Marque
• technique(s): immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable (1:100-1:200 (concentrated))
• isotype: IgG
• control: lung (squamous cell carcinoma), prostate
• shipped in: wet ice
• storage temp.: 2-8°C
• visualization: nuclear

Description

General description

p63 is a transcription factor that regulates many cell activities, including cell proliferation, maintenance, differentiation, adhesion, and apoptosis.¹ It has been found to be a sensitive and specific marker of myoepithelial and basal cell populations in prostate, breast, skin, and salivary gland. Additionally, p63 has also demonstrated immunohistochemical utility in identifying benign and malignant breast lesions.² In prostatic carcinomas, it can also be used to recognize benign glands adjacent to malignant glands.³ p63 can also be used to differentiate adenocarcinoma of the lungs, where it is usually negative, from squamous cell carcinoma, which can be useful for advanced stages of the carcinoma where surgery is no longer an option.⁴

Quality

United States - IVD
Canada - RUO
European Union - IVD
Japan - RUO

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

Preparation Note

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Other Notes

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Safety Information

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 2