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Propetamphos

PESTANAL®, analytical standard

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About This Item

Empirical Formula (Hill Notation):
C10H20NO4PS
CAS Number:
Molecular Weight:
281.31
Beilstein:
1979853
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

product line

PESTANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

agriculture
environmental

format

neat

storage temp.

2-8°C

SMILES string

CCNP(=S)(OC)O\C(C)=C\C(=O)OC(C)C

InChI

1S/C10H20NO4PS/c1-6-11-16(17,13-5)15-9(4)7-10(12)14-8(2)3/h7-8H,6H2,1-5H3,(H,11,17)/b9-7+

InChI key

BZNDWPRGXNILMS-VQHVLOKHSA-N

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General description

Propetamphos is an organophosphate insecticide, which acts by inhibiting acetylcholinesterase (AChE) enzyme activity.

Application

Propetamphos may be used as an analytical reference standard for the determination of the analyte in human tissues, fruits and crops by various chromatography techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Recommended products

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Legal Information

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Skull and crossbonesEnvironment

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 2 Inhalation - Acute Tox. 3 Dermal - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

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Determination of organophosphorus pesticide residues in human tissues by capillary gas chromatography--negative chemical ionization mass spectrometry analysis.
Russo MV, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 780(2), 431-441 (2002)
S García-Ortega et al.
Chemosphere, 83(8), 1117-1123 (2011-02-12)
Toxicity studies tend to use pure pesticides with single organisms. However, natural systems are complex and biological communities diverse. The organophosphate pesticide propetamphos (PPT) has been found exceeding regulatory limits (100 ng L(-1)) in rivers. We address whether solution properties
J A Wilson et al.
Medical and veterinary entomology, 8(3), 231-237 (1994-07-01)
A treated-surface test was used in a bioassay to detect insecticide resistance to the organophosphorus compounds diazinon and propetamphos, in larvae of field strains of Lucilia cuprina in New Zealand during 1990/91 and 1991/92 (December-April). Mean LC50s for both diazinon
K Dix et al.
Journal of biochemical toxicology, 7(4), 199-204 (1992-01-01)
Propetamphos [(E)-1-methylethyl 3-[[(ethylamino)methoxyphosphinothioyl]oxy]-2-butenoate], the active ingredient in Safrotin, is an organophosphate developed by Sandoz, Ltd. (Switzerland) as an insecticide (1). Although metabolism of propetamphos has been previously investigated (2,3), there is no pharmacokinetic data available in the literature. The current
Cindy M Cooke et al.
The Science of the total environment, 329(1-3), 197-213 (2004-07-21)
Two groups of chemicals are currently licensed for use in sheep dip products in the UK. These are organophosphate (OP) insecticides and synthetic pyrethroid (SP) insecticides. SPs are deemed to be less toxic to human health than OPs, although they

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