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3867

Sigma-Aldrich

Hydrocortisone

Steroid hormone of the adrenal cortex with anti-inflammatory properties.

Synonym(s):

Hydrocortisone, Cortisol

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About This Item

Empirical Formula (Hill Notation):
C21H30O5
CAS Number:
50-23-7
Molecular Weight:
362.46
MDL number:
MFCD00011654
UNSPSC Code:
12352200
NACRES:
NA.77

Quality Level

100

Assay

≥98% (TLC)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

color

white to off-white

solubility

ethanol: 15 mg/mL

shipped in

ambient

storage temp.

10-30°C

InChI

1S/C21H30O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,14-16,18,22,24,26H,3-8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1

InChI key

JYGXADMDTFJGBT-VWUMJDOOSA-N

General description

Steroid hormone of the adrenal cortex with anti-inflammatory properties.
Steroid synthesized by the adrenal cortex. Important in the regulation of protein, nucleic acid, and lipid metabolism. Pharmacologically, hydrocortisone is used to suppress the inflammatory response.

Biochem/physiol Actions

Cell permeable: no
Primary Target
Steroid hormone of the adrenal cortex with anti-inflammatory properties
Product does not compete with ATP.
Reversible: no

Warning

Toxicity: Carcinogenic / Teratogenic (D)

Preparation Note

Heating to 37°C may be required for complete solubilization.

Reconstitution

Following reconstitution, store in the refrigerator (4°C). Stock solutions are stable for up to 1 month at 4°C.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Health hazard
GHS08

Signal Word

Danger

Hazard Statements

H360Df,H373

Hazard Classifications

Repr. 1A - STOT RE 2

Target Organs

Adrenal gland,Bone marrow

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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