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LC/MS Analysis of Illicit Bath Salts on Ascentis® Express HILIC, Set 1

LC/MS Analysis of Illicit Bath Salts on Ascentis® Express HILIC, Set 1 application for HPLC

Materiais

Aplicação

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LC/MS Analysis of Illicit Bath Salts on Ascentis® Express HILIC, Set 2

application for HPLC

LC/MS Analysis of Illicit Bath Salts on Ascentis® Express HILIC, Set 3

application for HPLC

LC/MS Analysis of Illicit Bath Salts on Ascentis® Express HILIC, Set 4

application for HPLC

coluna analítica

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Ascentis® Express HILIC, 2.7 μm HPLC Column

2.7 μm particle size, L × I.D. 10 cm × 2.1 mm

padrão

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Methedrone hydrochloride solution

1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

3-Methoxymethcathinone hydrochloride

1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

MDPBP hydrochloride solution

1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

Naphyrone hydrochloride

1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

Pentylone hydrochloride

1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

CONDITIONS

column

Ascentis Express HILIC, 10 cm x 2.1 mm I.D., 2.7 μm particles (53939-U)

mobile phase

5 mM ammonium formate in [A] acetonitrile; [B] water; (98:2, A:B)

flow rate

0.6 mL/min

pressure

267 psi (18.4 bar)

column temp.

35 °C

detector

MS, ESI(+) TOF, Summed Ion Chromatogram

injection

2 μL

sample

500 ng/mL in acetonitrile

Descrição

Nota de análise

HILIC mode operation on an Ascentis Express column provided baseline resolution of these bath salts, including isobaric compounds. The highest quality LC-MS solvents were used to supply low background interference and low particulate contaminants for robust, trouble-free operation. Cerilliant CRMs provided reliable identification and quantification.

Informações legais

Ascentis is a registered trademark of Merck KGaA, Darmstadt, Germany