Metabolism of C-terminal pentapeptide of gastrin in the rat. Part IV. Catabolic pathways of the N-terminal BOC-14C-glycine fragment.

The catabolism of the 14C-labelled pentagastrin was investigated in rats. The following results were found: -- the labelled BOC-glycine fragment is split off the pentagastrin in the small intestine -- it is absorbed through the intestinal wall, and -- enters first the portal and then the systemic circulation.