Stereoselective one-pot, three-component synthesis of 4-aryltetrahydropyran via Prins-Friedel-Crafts reaction.

Stereoselective one-pot, three-component synthesis of 4-aryltetrahydropyran via Prins-Friedel-Crafts reaction.

The Journal of organic chemistry (2009-02-17)

U C Reddy, S Bondalapati, Anil K Saikia

PMID19216514

RESUMO

A diastereoselective one-pot, three-component Prins-Friedel-Crafts reaction was developed for the synthesis of 4-aryltetrahydropyran derivatives from the reaction of carbonyl compounds with homoallylic alcohol in the presence of arene promoted by boron trifluoride etherate.

MATERIAIS

Número do produto

Marca

Descrição do produto

175501

Sigma-Aldrich

Eterato dietílico de trifluoreto de boro, for synthesis

216607

Sigma-Aldrich

Eterato dietílico de trifluoreto de boro, purified by redistillation, ≥46.5% BF₃ basis