SRP8036

IL-36β mouse

>95% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized

• Sinônimo(s): Interleukin-1 family member 8, Interleukin-36β, Sentrin-specific protease 2
• Código UNSPSC: 12352202
• NACRES: NA.32

Propriedades

• Nome do produto: IL-36β mouse, recombinant, expressed in E. coli, untagged, >95% (SDS-PAGE)
• fonte biológica: mouse
• recombinante: expressed in E. coli
• conjugado: untagged
• Ensaio: >95% (SDS-PAGE)
• Formulário: lyophilized
• peso molecular: ~17 kDa
• embalagem: pkg of 10 μg
• Impurezas: <0.01 EU/μg endotoxin, tested
• cor: white
• nº de adesão UniProt: Q9D6Z6
• Condições de expedição: wet ice
• temperatura de armazenamento: −20°C
• Informações sobre genes: mouse ... Il36b(69677)

Descrição

Descrição geral

IL-36α (IL-1F6), IL-36β (IL-1F8) and IL-36γ (IL-1F9) bind to IL-36R (IL-1Rrp2) and IL-1RAcP, activating similar intracellular signals as IL-1. IL-36Ra inhibits the production of proinflammatory cytokines, including IL-12, IL-1β, IL-6, TNF-α and IL-23 induced by IL-36 in BMDC and CD4 T cells. Skin and dendritic cells are targets of the IL-36 interleukins leading to a Th1 response. These cytokines may represent potential targets for immune-mediated inflammatory conditions or, alternatively, could be used as adjuvants in vaccination.

forma física

Lyophilized from PBS and 0.5% trehalose.

Reconstituição

Reconstitute with 100 μL deionized water.

Outras notas

IL-36beta (mouse) (aa 31-183) is untagged.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 2
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable