SRP4561

Resistin from rat

recombinant, expressed in E. coli, ≥95% (SDS-PAGE)

• Sinônimo(s): ADSF, Adipose tissue-specific secretory factor, C/EBP-ε-regulated myeloid-specific secreted cysteine-rich protein, Cysteine-rich secreted protein A12-α-like 2, Cysteine-rich secreted protein FIZZ3, RSTN
• Número MDL: MFCD03792461
• Código UNSPSC: 12352200
• NACRES: NA.32

Propriedades

• fonte biológica: rat
• recombinante: expressed in E. coli
• Ensaio: ≥95% (SDS-PAGE)
• Formulário: lyophilized
• peso molecular: ~11.9 kDa
• embalagem: pkg of 25 μg
• Impurezas: endotoxin, tested
• nº de adesão NCBI: NP_653342
• nº de adesão UniProt: Q8CJE0
• Condições de expedição: wet ice
• temperatura de armazenamento: −20°C
• Informações sobre genes: rat ... Retn(246250)

Descrição

Descrição geral

Resistin is a new member to of the family of adipocyte-secreted proteins. The biological functions of resistin, as well as its molecular target, are largely unknown. Whether it promotes or antagonizes insulin action is still unclear. Recombinant rat Resistin is an 11.9 kDa protein consisting of 94 amino acid residues and 16 additional amino acids residues-His Tag.
Resistin is an adipocytokine secreted by fat tissues and is localized to pancreatic α-cells in rat.

Aplicação

Resistin from rat has been used to study the effect of resistin on gonadotropins and local ovarian hormone-induced steroidogenesis.

Ações bioquímicas/fisiológicas

Resistin mediates energy homeostasis and inflammation process. Upregulation of resistin is observed in obesity. It is also known to increase blood glucose level and might promote insulin resistance. Thus, it might influence type 2 diabetes. Resistin might be linked to insulin resistance mediated myocardial infarction (MI). In rats, overexpression of resistin is observed in myocardial infarction and cardiac dysfunction.

forma física

Lyophilized from 20 mM Tris, pH 8.0.

Reconstituição

Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.

Reconstitute in water to a concentration of 0.1-1.0 mg/mL. This solution can then be diluted into other aqueous buffers.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable