SBR00094

Valnemulin hydrochloride

≥96% (HPLC), powder

• Sinônimo(s): Econor
• Fórmula empírica (Notação de Hill): C₃₁H₅₂N₂O₅S · HCl
• Número CAS: 133868-46-9
• Peso molecular: 601.28
• Número MDL: MFCD08458958
• Código UNSPSC: 51101500

Propriedades

• Nível de qualidade: 100
• Ensaio: ≥96% (HPLC)
• Formulário: powder
• espectro de atividade do antibiótico: Gram-negative bacteria; Gram-positive bacteria
• Modo de ação: protein synthesis | inhibits
• Condições de expedição: ambient
• temperatura de armazenamento: −20°C
• cadeia de caracteres SMILES: CC(C)[C@@H](N)C(NCC(C)(C)SCC(O[C@H]1[C@](C)([C@@H]2C)[C@@]3([H])[C@@](CC2)(CCC3=O)[C@@H](C)[C@H](O)[C@](C)(C=C)C1)=O)=O.Cl
• InChI: 1S/C31H52N2O5S.ClH/c1-10-29(8)15-22(38-23(35)16-39-28(6,7)17-33-27(37)24(32)18(2)3)30(9)19(4)11-13-31(20(5)26(29)36)14-12-21(34)25(30)31;/h10,18-20,22,24-26,36H,1,11-17,32H2,2-9H3,(H,33,37);1H/t19-,20+,22-,24-,25+,26+,29-,30+,31+;/m1./s1
• chave InChI: MFBPRQKHDIVLOJ-AFFLPQGKSA-N

Descrição

Descrição geral

Valnemulin Hydrochloride is an antibiotic which belongs to the class of compounds known as pleuromutilins. It is a semisynthetic derivative of the naturally occurring antibiotic tiamulin. Valnemulin Hydrochloride has activity against various Gram-positive and some Gram-negative bacteria, including Mycoplasma and some anaerobic bacteria, as well as the protozoan parasite Eimeria.

Ações bioquímicas/fisiológicas

Valnemulin Hydrochloride inhibits bacterial protein synthesis by binding to the 50S subunit of the bacterial ribosome. More specifically, it binds to the peptidyl transferase center of the ribosome and interferes with the transfer of amino acids to growing polypeptide chains, leading to the inhibition of protein synthesis and bacterial death.

Informações de segurança

• Pictogramas: GHS07
• Palavra indicadora: Warning
• Frases de perigo: H302
• Declarações de precaução: P264 - P270 - P301 + P312 - P501
• Classificações de perigo: Acute Tox. 4 Oral
• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable