SAB5702784

Anti-GABARAPL2 Antibody, clone 8Z8M8, Rabbit Monoclonal

• Sinônimo(s): ATG8, ATG8C, GATE-16, GATE16, GEF-2, GEF2
• Código UNSPSC: 12352203
• NACRES: NA.46
• clone: 8Z8M8, monoclonal
• application: WB
• reatividade de espécies: human, rat, rat
• técnica(s): western blot: 1:500 - 1:2000

Propriedades

• fonte biológica: rabbit
• Nível de qualidade: 100
• Materiais: colorless
• clone: 8Z8M8, monoclonal
• Formulário: liquid
• peso molecular: 16 kDa
• reatividade de espécies: human, rat, rat
• concentração: 0.3 mg/mL
• técnica(s): western blot: 1:500 - 1:2000
• cor: colorless
• Isotipo: IgG
• sequência de imunogênio: GSQIVDIDKRKYLVPSDITVAQFMWIIRKRIQLPSEKAIFLFVDKTVPQSSLTMGQLYEKEKDEDGFLYVAYSGENTFGF
• nº de adesão UniProt: P60520
• Condições de expedição: wet ice
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: human ... GABARAPL2(11345)

Descrição

Descrição geral

Ubiquitin-like modifier involved in intra-Golgi traffic (By similarity. Modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation (By similarity. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1 (By similarity. Involved in autophagy. Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation.

Imunogênio

A synthetic peptide corresponding to a sequence within amino acids 38-117 of human GABARAPL2 (P60520).

PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Aplicação

WB

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 1