SAB5702655

[KO Validated]Anti-HDAC8 Antibody, clone 1O2Y5, Rabbit Monoclonal

• Sinônimo(s): CDA07, CDLS5, HD8, HDACL1, MRXS6, RPD3, WTS
• Código UNSPSC: 12352203
• NACRES: NA.46
• clone: 1O2Y5, monoclonal
• application: IF; IHC; IP; WB
• reatividade de espécies: human, rat, rat
• técnica(s): immunofluorescence: 1:50 - 1:200; immunohistochemistry: 1:50 - 1:200; immunoprecipitation (IP): 1:50 - 1:200; western blot: 1:500 - 1:2000

Propriedades

• fonte biológica: rabbit
• Nível de qualidade: 100
• Materiais: colorless
• clone: 1O2Y5, monoclonal
• Formulário: liquid
• peso molecular: 42 kDa
• reatividade de espécies: human, rat, rat
• concentração: 0.3 mg/mL
• técnica(s): immunofluorescence: 1:50 - 1:200; immunohistochemistry: 1:50 - 1:200; immunoprecipitation (IP): 1:50 - 1:200; western blot: 1:500 - 1:2000
• cor: colorless
• Isotipo: IgG
• sequência de imunogênio: MEEPEEPADSGQSLVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDDDHPDSIEYGLGY
• nº de adesão UniProt: Q9BY41
• Condições de expedição: wet ice
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: human ... HDAC8(55869)

Descrição

Descrição geral

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]

Imunogênio

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human HDAC8 (Q9BY41).

PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Aplicação

WB, IHC, IF/ICC, IP

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 1