SAB4702047

Monoclonal Anti-CD81 APC-Cyanine7 produced in mouse

• Sinônimo(s): CVID6, S5.7, TAPA1, TSPAN28
• Código UNSPSC: 12352203

Propriedades

• conjugado: APC-Cy7 conjugate
• Nível de qualidade: 100
• tipo de produto de anticorpo: primary antibodies
• clone: M38, monoclonal
• forma: buffered aqueous solution
• reatividade de espécies: ( Human), rabbit, ( Cat)
• técnica(s): flow cytometry: suitable
• Isotipo: IgG1
• nº de adesão UniProt: P60033
• temperatura de armazenamento: 2-8°C
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: human ... CD81(975)

Descrição

Descrição geral

CD81 (TAPA-1), a member of the tetraspanin family, is expressed on virtually all nucleated cells, but above all on germinal center B cells. CD81 forms complexes with other tetraspanin proteins, integrins, coreceptors, MHC class I and II molecules, and influences adhesion, morphology, activation, proliferation and differentiation of B, T and other cells, e.g. in muscles CD81 promotes cell fusion and myotube maintenance. CD81 has been also identified as a receptor for the hepatitis C virus.

Especificidade

The antibody M38 reacts with an extracellular epitope of CD81, a 25 kDa member of the tetraspanin family, expressed on majority of cells.

Imunogênio

MOLT-4 (human T-ALL cell line)

forma física

Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Nota de preparo

Purified antibody is conjugated with activated tandem dye of allophycocyanin-cyanine 7 (APC-Cy7) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Armazenamento e estabilidade

Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Outras notas

The antibody solution should be gently mixed before use.

Informações de segurança

• Código de classe de armazenamento: 12 - Non Combustible Liquids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable