SAB4700301
Monoclonal Anti-HLA-E antibody produced in mouse
clone MEM-E/06, purified immunoglobulin, buffered aqueous solution
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About This Item
Código UNSPSC:
12352203
NACRES:
NA.41
fonte biológica
mouse
Nível de qualidade
conjugado
unconjugated
forma do anticorpo
purified immunoglobulin
tipo de produto de anticorpo
primary antibodies
clone
MEM-E/06, monoclonal
Formulário
buffered aqueous solution
reatividade de espécies
nonhuman primates, human
concentração
1 mg/mL
técnica(s)
flow cytometry: suitable
Isotipo
IgG1
nº de adesão NCBI
nº de adesão UniProt
Condições de expedição
wet ice
temperatura de armazenamento
2-8°C
modificação pós-traducional do alvo
unmodified
Informações sobre genes
human ... HLA-E(3133)
Descrição geral
The antibody MEM-E/06 recognized native surface-expressed HLA-E, but not denaturated heavy chain of HLA-E. HLA-E belongs to the MHC Class I molecules (MHC Class Ib; nonclassical) and it is expressed on many types of the human cells.
Imunogênio
Bacterially expressed recombinant HLA-E refolded with beta2-microglobulin and peptide
Aplicação
The reagent is designed for Flow Cytometry analysis. Suggested working dilution for Flow Cytometry is 5 μg/mL of sample. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator.
Características e benefícios
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
forma física
Solution in Tris buffered saline, pH 8.0, with 15 mM sodium azide.
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Código de classe de armazenamento
10 - Combustible liquids
Classe de risco de água (WGK)
WGK 1
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
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Tsufit Gonen-Gross et al.
Journal of immunology (Baltimore, Md. : 1950), 175(8), 4866-4874 (2005-10-08)
For a proper development of the placenta, maternal NK cells should not attack the fetal extravillous cytotrophoblast cells. This inhibition of maternal NK cells is partially mediated via the nonclassical MHC class I molecule HLA-G. Recently, we demonstrated that HLA-G
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Journal of applied physiology (Bethesda, Md. : 1985), 116(12), 1582-1592 (2014-05-03)
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American journal of physiology. Heart and circulatory physiology, 307(8), H1111-H1119 (2014-08-17)
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