SAB4600176
Anti-Mouse IgG (H+L), highly cross-adsorbed, CF™ 647 antibody produced in donkey
~2 mg/mL, affinity isolated antibody
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About This Item
Código UNSPSC:
12352203
NACRES:
NA.46
Produtos recomendados
fonte biológica
donkey
Nível de qualidade
conjugado
CF™ 647 conjugate
forma do anticorpo
affinity isolated antibody
tipo de produto de anticorpo
secondary antibodies
clone
polyclonal
Formulário
buffered aqueous solution
reatividade de espécies
mouse
concentração
~2 mg/mL
técnica(s)
flow cytometry: 1-10 μg/mL
immunocytochemistry: suitable
immunohistochemistry: suitable
indirect immunofluorescence: 1-10 μg/mL
fluorescência
λex 650 nm; λem 665 nm
Condições de expedição
dry ice
temperatura de armazenamento
−20°C
modificação pós-traducional do alvo
unmodified
Descrição geral
Immunoglobulin G (IgG) is a glycoprotein antibody with two equivalent light chains and a pair of identical heavy chains. CF™ 647 is an organic cyanine dye useful in fluorescent microscopy studies. Antibody–CF™ 647 conjugates are affinity-purified antibodies labeled with a far-red fluorescent dye, CF™ 647. CF™ dyes are excellent alternatives to Alexa Fluor™ dyes for antibody labeling with exceptional brightness, photostability, and/or specificity.
Especificidade
Binds all mouse IgGs (minimal cross-reaction with bovine, chicken, goat, guinea pig, hamster, horse, human, rabbit and sheep serum proteins)
Imunogênio
mouse IgG (H+L)
Ações bioquímicas/fisiológicas
Immunoglobulin G (IgG) on pepsin digestion results in fragment crystallizable (Fc), which comprises the H chain constant region. Papain digestion of IgG results in the generation of fragment antigen-binding (Fab) comprising of one complete L chain and a variable and CH1 region of H chain.
Características e benefícios
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
forma física
Supplied in phosphate buffered saline with 0.05% sodium azide, 50% glycerol and 2 mg/mL bovine serum albumin.
Nota de preparo
Protect from light.
Informações legais
This product is distributed by Sigma-Aldrich Co. under the authorization of Biotium, Inc. This product is covered by one or more US patents and corresponding patent claims outside the US patents or pending applications owned or licensed by Biotium, Inc. including without limitation: 12/334,387; 12/607,915; 12/699,778; 12/850,578; 61/454,484. In consideration of the purchase price paid by the buyer, the buyer is hereby granted a limited, non-exclusive, non-transferable license to use only the purchased amount of the product solely for the buyer′s own internal research in a manner consistent with the accompanying product literature. Except as expressly granted herein, the sale of this product does not grant to or convey upon the buyer any license, expressly, by implication or estoppel, under any patent right or other intellectual property right of Biotium, Inc. Buyer shall not resell or transfer this product to any third party, or use the product for any commercial purposes, including without limitation, any diagnostic, therapeutic or prophylactic uses. This product is for research use only. Any other uses, including diagnostic uses, require a separate license from Biotium, Inc. For information on purchasing a license to use this product for purposes other than research, contact Biotium, Inc., 3159 Corporate Place, Hayward, CA 94545, Tel: (510) 265-1027. Fax: (510) 265-1352. Email: btinfo@biotium.com.
ALEXA FLUOR is a trademark of Life Technologies
CF is a trademark of Biotium, Inc.
Exoneração de responsabilidade
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Código de classe de armazenamento
10 - Combustible liquids
Classe de risco de água (WGK)
WGK 2
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
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Blue-conversion of Organic Dyes Produces Artifacts in Multicolor Fluorescence Imaging
Kim DH, et al.
Chemical Science null
Harry W Schroeder et al.
The Journal of allergy and clinical immunology, 125(2 Suppl 2), S41-S52 (2010-03-05)
Immunoglobulins are heterodimeric proteins composed of 2 heavy and 2 light chains. They can be separated functionally into variable domains that bind antigens and constant domains that specify effector functions, such as activation of complement or binding to Fc receptors.
Gestur Vidarsson et al.
Frontiers in immunology, 5, 520-520 (2014-11-05)
Of the five immunoglobulin isotypes, immunoglobulin G (IgG) is most abundant in human serum. The four subclasses, IgG1, IgG2, IgG3, and IgG4, which are highly conserved, differ in their constant region, particularly in their hinges and upper CH2 domains. These
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