SAB4504665

Anti-phospho-BL-CAM (pTyr⁸⁰⁷) antibody produced in rabbit

affinity isolated antibody

• Código UNSPSC: 12352203
• NACRES: NA.41

Propriedades

• fonte biológica: rabbit
• Nível de qualidade: 100
• conjugado: unconjugated
• forma do anticorpo: affinity isolated antibody
• tipo de produto de anticorpo: primary antibodies
• clone: polyclonal
• Formulário: buffered aqueous solution
• peso molecular: antigen 95 kDa
• reatividade de espécies: mouse, rat, human
• concentração: ~1 mg/mL
• técnica(s): ELISA: 1:40000; western blot: 1:500-1:1000
• nº de adesão NCBI: P20273
• nº de adesão UniProt: P20273
• Condições de expedição: wet ice
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: phosphorylation (pTyr807)
• Informações sobre genes: human ... CD22(933)

Descrição

Descrição geral

CD22 (cluster of differentiation 22) is a 140 kDa single-spanning membrane glycoprotein present on the surface of B cells. This gene belongs to the sialic acid-binding Ig-type lectin (Siglec) family. CD22 is mapped to human chromosome 19q13.

Imunogênio

The antiserum was produced against synthesized peptide derived from human BL-CAM around the phosphorylation site of Tyr807.

Immunogen Range: 776-825

Ações bioquímicas/fisiológicas

CD22 (cluster of differentiation 22) helps to maintain B-cell homeostasis. This molecule act as an inhibitory coreceptor of the BCR (B cell receptor). CD22 is considered as a response regulator to control several aspects of B cell functions. Deficiency in CD22 or its pathways may contribute to autoimmunity.

Características e benefícios

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forma física

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable