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Merck
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Key Documents

SAB4504393

Sigma-Aldrich

Anti-phospho-eNOS (pSer1176) antibody produced in rabbit

affinity isolated antibody

Sinônimo(s):

Anti-ECNOS, Anti-eNOS

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About This Item

Código UNSPSC:
12352203
NACRES:
NA.41

fonte biológica

rabbit

conjugado

unconjugated

forma do anticorpo

affinity isolated antibody

tipo de produto de anticorpo

primary antibodies

clone

polyclonal

forma

buffered aqueous solution

peso molecular

antigen 133 kDa

reatividade de espécies

rat, human, mouse

concentração

~1 mg/mL

técnica(s)

ELISA: 1:20000
western blot: 1:500-1:1000

nº de adesão NCBI

P29474

nº de adesão UniProt

P29474

Condições de expedição

wet ice

temperatura de armazenamento

−20°C

modificação pós-traducional do alvo

phosphorylation (pSer1176)

Informações sobre genes

human ... NOS3(4846)

Descrição geral

Nitric oxide synthase 3 (NOS3), also known as endothelial nitric oxide synthase (eNOS), is encoded by the gene mapped to human chromosome 7q35-36. The gene consists of 26 exons.

Imunogênio

The antiserum was produced against synthesized peptide derived from human eNOS around the phosphorylation site of Ser1176.

Immunogen Range: 1144-1193

Ações bioquímicas/fisiológicas

Nitric oxide synthase 3 (NOS3) has been studied as a modulator of vascular function and is involved in the production of nitric oxide. Defects in the enzyme expression have been shown to be associated with coronary artery disease.

Características e benefícios

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

forma física

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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Visite a Biblioteca de Documentos

Association between three eNOS polymorphisms and intracranial aneurysms risk: a meta-analysis.
Yang C, et al.
Medicine, 94(4) (2015)
Association between three eNOS polymorphisms and intracranial aneurysms risk: a meta-analysis.
Yang C, et al.
Medicine, 94(4) (2015)
Marwa Ben Ali et al.
Genetic testing and molecular biomarkers, 19(4), 203-208 (2015-03-10)
Nitric oxide (NO), produced by the enzyme endothelial nitric oxide synthase (eNOS), has critical roles in the regulation of vascular homeostasis and prevention of atherogenesis by inhibiting leukocytes, platelet activation, and smooth muscle cell proliferation. There is strong experimental and
Sherif Hafez et al.
Translational stroke research, 11(4), 851-860 (2019-12-21)
Physical exercise is known to reduce cardiovascular risk but its role in ischemic stroke is not clear. It was previously shown that an acute single bout of exercise reduced increased eNOS activation in the heart and reduced myocardial infarction. However
Bing Yi et al.
Arteriosclerosis, thrombosis, and vascular biology, 35(10), 2153-2160 (2015-08-22)
Endothelial nitric oxide synthase (eNOS) is an important regulator of vascular function and its expression is regulated at post-transcriptional levels through a yet unknown mechanism. The purpose of this study is to elucidate the post-transcriptional factors regulating eNOS expression and
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