SAB4501401

Anti-HMGB1 antibody produced in rabbit

affinity isolated antibody

• Sinônimo(s): HMG-1, HMG1, High mobility group protein 1, High mobility group protein B1
• Número MDL: MFCD02263062
• Código UNSPSC: 12352203
• NACRES: NA.41

Propriedades

• fonte biológica: rabbit
• Nível de qualidade: 100
• conjugado: unconjugated
• forma do anticorpo: affinity isolated antibody
• tipo de produto de anticorpo: primary antibodies
• clone: polyclonal
• Formulário: buffered aqueous solution
• peso molecular: antigen 24 kDa
• reatividade de espécies: rat, human, mouse
• concentração: ~1 mg/mL
• técnica(s): ELISA: 1:20000; western blot: 1:500-1:1000
• nº de adesão NCBI: P09429
• nº de adesão UniProt: P09429
• Condições de expedição: wet ice
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: human ... HMGB1(3146)

Descrição

Descrição geral

Anti-HMGB1 Antibody detects endogenous levels of total HMGB1 protein.

High mobility group box 1 (HMGB1) is a nuclear protein that belongs to the damage-associated molecular pattern (DAMP) family. It is located on human chromosome 13q12.

Imunogênio

The antiserum was produced against synthesized peptide derived from human HMGB1.

Immunogen Range: 131-180

Ações bioquímicas/fisiológicas

High mobility group box 1 (HMGB1) is involved in bone remodeling and ectopic calcification pathogenesis. It initiates neuroinflammation after epileptogenic injuries. HMGB1 also binds to chromatin and modulates gene transcription.

Características e benefícios

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

forma física

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): nwg
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable